Using the TIDieR checklist to describe the intervention of the Sedation and Weaning in Children (SANDWICH) trial

Lyvonne N. Tume*, Bronagh Blackwood, Daniel F. McAuley, Kevin Morris, Mark J. Peters, Joanne Jordan, Timothy Simon Walsh, Lisa McIlmurray

*Corresponding author for this work

Research output: Contribution to journalArticle (journal)peer-review

2 Citations (Scopus)
27 Downloads (Pure)


Background: Published reports of complex interventions in randomized controlled trials often lack sufficient detail to allow trial replication and adoption into practice. Aim: The aim of this paper is to describe our experience of using the Template for Intervention Description and Replication (TIDieR) checklist in reporting a recent trial of sedation and ventilation weaning in critically ill children (the Sedation and Weaning in Children [SANDWICH] trial). Methods: The TIDieR 12-point checklist has been used to detail and describe the specific SANDWICH trial intervention and methods of implementation. Results/Discussion: Overall, we found the checklist a useful tool to direct and ensure consistency of reporting of our complex intervention used in a multi-centre clinical trial. We experienced some minor limitations in classifying training materials and delivery mode into one item because of the overlapping nature of this component. Conclusion: Using the TIDieR checklist to report complex interventions tested in trials provides a structured, systematic way of describing necessary detail. This allows clinicians to understand the theory behind the intervention, how it should be delivered, and the resources required. Relevance to Clinical Practice: The SANDWICH intervention had a significant beneficial effect on reducing time on ventilation for children. The detailed description of the team-based intervention will aid replication, implementation and monitoring of fidelity in other paediatric intensive care units.

Original languageEnglish
JournalNursing in Critical Care
Early online date22 Jun 2022
Publication statusPublished - 22 Jun 2022


  • child
  • complex intervention
  • intensive care
  • mechanical ventilation
  • neonate
  • paediatric


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