Transglutaminase 1 Replacement Therapy Successfully Mitigates the Autosomal Recessive Congenital Ichthyosis Phenotype in Full-Thickness Skin Disease Equivalents

Roswitha Plank, Guy Yealland, Enrico Miceli, Dulce Lima Cunha, Patrick Graff, Sari Thomforde, Robert Gruber, Verena Moosbrugger-Martinz, Katja Eckl, Marcelo Calderón, Hans Christian Hennies, Sarah Hedtrich

Research output: Contribution to journalArticlepeer-review

11 Citations (Scopus)
115 Downloads (Pure)

Abstract

This is a letter to the editor
Original languageEnglish
Pages (from-to)1191-1195
Number of pages5
JournalJournal of Investigative Dermatology
Volume139
Issue number5
Early online date15 Nov 2018
DOIs
Publication statusPublished - 1 May 2019

Keywords

  • ARCI
  • Tgase-1
  • enzyme-replacement therapy
  • nanoparticles
  • 3D skin modelling
  • ichthyosis
  • orphan drug
  • tNG
  • TWEL

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