The role of molecular strategies in the evaluation of surgical margins in oropharyngeal squamous cell carcinoma

A N Kanatas; A T Harris; M Messenger; D Houghton; Simon N Rogers

doi:10.1007/s12156-009-0020-9

The role of molecular strategies in the evaluation of surgical margins in oropharyngeal squamous cell carcinoma

A N Kanatas, A T Harris, M Messenger, D Houghton, Simon N Rogers

Research output: Contribution to journal › Article (journal) › peer-review

Abstract

The recurrence of a tumour at the resection margins in head and neck squamous cell carcinoma (HNSCC) has profound implications on the morbidity and mortality of the patient. At present HNSCC does not undergo any form of molecular analysis to aid treatment strategy and prognosticate for those individuals at higher risk of recurrence. This article aims to review current research into molecular strategies for tumour evaluation, highlighting conflicting evidence and possible novel concepts for further exploration.

Original language	English
Pages (from-to)	161-167
Journal	Oncology Reviews
Volume	3
Issue number	3
DOIs	https://doi.org/10.1007/s12156-009-0020-9
Publication status	Published - 2009

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title = "The role of molecular strategies in the evaluation of surgical margins in oropharyngeal squamous cell carcinoma",

abstract = "The recurrence of a tumour at the resection margins in head and neck squamous cell carcinoma (HNSCC) has profound implications on the morbidity and mortality of the patient. At present HNSCC does not undergo any form of molecular analysis to aid treatment strategy and prognosticate for those individuals at higher risk of recurrence. This article aims to review current research into molecular strategies for tumour evaluation, highlighting conflicting evidence and possible novel concepts for further exploration.",

author = "Kanatas, {A N} and Harris, {A T} and M Messenger and D Houghton and Rogers, {Simon N}",

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AU - Harris, A T

AU - Messenger, M

AU - Houghton, D

AU - Rogers, Simon N

PY - 2009

Y1 - 2009

N2 - The recurrence of a tumour at the resection margins in head and neck squamous cell carcinoma (HNSCC) has profound implications on the morbidity and mortality of the patient. At present HNSCC does not undergo any form of molecular analysis to aid treatment strategy and prognosticate for those individuals at higher risk of recurrence. This article aims to review current research into molecular strategies for tumour evaluation, highlighting conflicting evidence and possible novel concepts for further exploration.

AB - The recurrence of a tumour at the resection margins in head and neck squamous cell carcinoma (HNSCC) has profound implications on the morbidity and mortality of the patient. At present HNSCC does not undergo any form of molecular analysis to aid treatment strategy and prognosticate for those individuals at higher risk of recurrence. This article aims to review current research into molecular strategies for tumour evaluation, highlighting conflicting evidence and possible novel concepts for further exploration.

U2 - 10.1007/s12156-009-0020-9

DO - 10.1007/s12156-009-0020-9

M3 - Article (journal)

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VL - 3

SP - 161

EP - 167

JO - Oncology Reviews

JF - Oncology Reviews

IS - 3

ER -

The role of molecular strategies in the evaluation of surgical margins in oropharyngeal squamous cell carcinoma

Abstract

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