Abstract
Angiotensin II Receptor blockers (ARBs) are an important addition to the current range of medications available for treating a wide spectrum of diseases including cardiovascular diseases. Coronary heart disease (CHD) is the most common cause of death in the United Kingdom and worldwide. More importantly, the presence of the metabolic syndrome and the likelihood of diabetes mellitus taking on epidemic proportions in the years to come all threaten to maintain the mortality rate due to CHD. This review article focuses on the clinical studies that have helped define the trends in the usage of these agents in the prevention and treatment of diabetes mellitus and its complications and also explores possible mechanisms of action and future developments.
Original language | English |
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Pages (from-to) | 617-629 |
Number of pages | 13 |
Journal | Diabetes, Obesity and Metabolism |
Volume | 9 |
Issue number | 5 |
DOIs | |
Publication status | Published - 21 Aug 2006 |
Keywords
- Angiotensin II receptor blockers
- Diabetes mellitus
- Microalbuminuria
- Renal disease
- Rennin angiotensin system