The role of angiotensin II type 1 receptor blockers in the prevention and management of diabetes mellitus

Gershan Mathur*, B. Noronha, E. Rodrigues, G. Davis

*Corresponding author for this work

Research output: Contribution to journalReview articlepeer-review

8 Citations (Scopus)

Abstract

Angiotensin II Receptor blockers (ARBs) are an important addition to the current range of medications available for treating a wide spectrum of diseases including cardiovascular diseases. Coronary heart disease (CHD) is the most common cause of death in the United Kingdom and worldwide. More importantly, the presence of the metabolic syndrome and the likelihood of diabetes mellitus taking on epidemic proportions in the years to come all threaten to maintain the mortality rate due to CHD. This review article focuses on the clinical studies that have helped define the trends in the usage of these agents in the prevention and treatment of diabetes mellitus and its complications and also explores possible mechanisms of action and future developments.

Original languageEnglish
Pages (from-to)617-629
Number of pages13
JournalDiabetes, Obesity and Metabolism
Volume9
Issue number5
DOIs
Publication statusPublished - 21 Aug 2006

Keywords

  • Angiotensin II receptor blockers
  • Diabetes mellitus
  • Microalbuminuria
  • Renal disease
  • Rennin angiotensin system

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