The Reproducibility of Blood Acid Base Responses in Male Collegiate Athletes Following Individualised Doses of Sodium Bicarbonate: A Randomised Controlled Crossover Study

Lewis Gough, Sanjoy Deb, Andy Sparks, Lars McNaughton

Research output: Contribution to journalArticle

16 Citations (Scopus)
36 Downloads (Pure)

Abstract

Abstract: Current evidence has suggested an individualised NaHCO3 ingestion strategy may be the most appropriate method to elicit a state of peak alkalosis. Such a strategy has displayed large interindividual variation (range 10-180 min) and if such a strategy is to be practically applied, the blood analyte response needs to be reproducible. Therefore, this study aimed to evaluate the reproducibility of blood pH, HCO3- and Na+ following acute NaHCO3 ingestion on more than one occasion. Fifteen team sports players completed six randomised trials entailing ingestion of 0.2 g.kg-1 BM NaHCO3 (SBC2a and b) twice, 0.3 g.kg-1 BM NaHCO3 (SBC3a and b) twice, or two control trials (CON1a and b) on separate days. Blood analysis included pH, HCO3- and Na+ prior to and at regular time points following NaHCO3 ingestion over a three hour period. Compared to pH, a greater relationship for HCO3- in both time to peak (HCO3- SBC2 = 0.772, P = 0.003, SBC3 = 0.942, P <0.001; pH SBC2 = 0.618, P = 0.044 SBC3 = 0.712, P = 0.016) and absolute change (HCO3- SBC2 = 0.890, P <0.001, SBC3 = 0.755, P = 0.008; pH SBC2 = 0.842, P = 0.001, SBC3 = 0.624, P = 0.041) was observed. Our results indicate both time to peak and absolute change in HCO3- is more reliable compared to pH. Future work should utilise an individualised NaHCO3 ingestion strategy based on HCO3- responses and evaluate the effects on exercise performance.
Original languageEnglish
Pages (from-to)2117-2127
JournalSports Medicine
Volume47
Issue number10
Early online date22 Feb 2017
DOIs
Publication statusPublished - Oct 2017

Keywords

  • Buffers
  • bicarbonate
  • alkalosis
  • metabolism
  • individual response

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