Syllogistic reasoning performance in MDMA (ecstasy) users

C Montgomery, J. Fisk, R. Newcombe, M. Wareing, P. Murphy

Research output: Contribution to journalArticle (journal)peer-review

19 Citations (Scopus)


Previous research has demonstrated working memory and executive deficits in recreational users of MDMA (3,4-methylenedioxymethamphetamine; Ecstasy). In turn, both of these constructs have been implicated in syllogistic reasoning performance. Twenty-two MDMA users (mean age=21.36) and 26 MDMA nonuser controls (mean age=21.31) were tested on syllogisms of varying difficulty and on measures of working memory and executive functioning. MDMA users were significantly impaired in aspects of syllogistic reasoning, and the effect remained significant after the authors controlled for the use of other drugs. However, the MDMA-related variance was reduced to below statistical significance following control for group differences in working memory span. The results are consistent with the possibility that MDMA-related deficits in aspects of executive functioning result in impaired reasoning performance among MDMA users.
Original languageEnglish
Pages (from-to)137-145
JournalExperimental & Clinical Psychopharmacology
Issue number2
Publication statusPublished - May 2005


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