Sulcal morphology and volume of Broca’s area linked to handedness and sex

Joanne L Powell, Graham J Kemp, Neil Roberts, Marta Garcia-Finana

Research output: Contribution to journalArticle

11 Citations (Scopus)

Abstract

We investigated the effect of handedness and sex on: (i) sulcal contours defining PO and PTR and (ii) volume estimates of PO and PTR subfields in 40 left- and 42 right-handers. Results show an effect of handedness on discontinuity of the inferior frontal sulcus (IFS: P < 0.01). Discontinuity of IFS was observed in: 43% left- and 62% right hemispheres in right-handers and in 65% left- and 48% right-hemispheres in left-handers. PO volume asymmetry was rightward in left-handed males (P = 0.007) and females (P = 0.02), showed a leftward trend in right-handed males (P = 0.06), and was non-asymmetrical in right-handed females (P = 0.96, i.e. left- and right-hemisphere PO volumes did not differ significantly). PO volume asymmetry in males differed significantly between handedness groups (P = 0.001). Findings indicate a high degree of variability in the sulcal contours of PO and PTR and volume asymmetry of PO: the factors sex and handedness can explain some of this variability.
Original languageEnglish
Pages (from-to)206-218
JournalBrain and Language
Volume121
Issue number3
DOIs
Publication statusPublished - 2012

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Functional Laterality
asymmetry
Sex Factors
Prefrontal Cortex
trend
Broca Area
Handedness
Broca's Area
Group
Right Hemisphere
Asymmetry
Discontinuity

Cite this

Powell, Joanne L ; Kemp, Graham J ; Roberts, Neil ; Garcia-Finana, Marta. / Sulcal morphology and volume of Broca’s area linked to handedness and sex. In: Brain and Language. 2012 ; Vol. 121, No. 3. pp. 206-218.
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Sulcal morphology and volume of Broca’s area linked to handedness and sex. / Powell, Joanne L; Kemp, Graham J; Roberts, Neil; Garcia-Finana, Marta.

In: Brain and Language, Vol. 121, No. 3, 2012, p. 206-218.

Research output: Contribution to journalArticle

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AB - We investigated the effect of handedness and sex on: (i) sulcal contours defining PO and PTR and (ii) volume estimates of PO and PTR subfields in 40 left- and 42 right-handers. Results show an effect of handedness on discontinuity of the inferior frontal sulcus (IFS: P < 0.01). Discontinuity of IFS was observed in: 43% left- and 62% right hemispheres in right-handers and in 65% left- and 48% right-hemispheres in left-handers. PO volume asymmetry was rightward in left-handed males (P = 0.007) and females (P = 0.02), showed a leftward trend in right-handed males (P = 0.06), and was non-asymmetrical in right-handed females (P = 0.96, i.e. left- and right-hemisphere PO volumes did not differ significantly). PO volume asymmetry in males differed significantly between handedness groups (P = 0.001). Findings indicate a high degree of variability in the sulcal contours of PO and PTR and volume asymmetry of PO: the factors sex and handedness can explain some of this variability.

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