Self-assembly of biomolecules: AFM study of F-actin on unstructured and nanostructured surfaces

Marina Naldi, Elena Vasina, Serban Dobroiu, Luminita Paraoan, Dan V. Nicolau, Vincenza Andrisano*

*Corresponding author for this work

Research output: Chapter in Book/Report/Conference proceedingConference proceeding (ISBN)peer-review

3 Citations (Scopus)

Abstract

Advanced nanofabrication is capable of producing structures in the vicinity of the size of large biomolecules or their aggregates. Some of these protein aggregates emerge as having deleterious medical effects, e.g., degenerative diseases, or essential for biological processes, e.g., actin, cytoskeleton formation. Therefore it became possible, and important, to think of ways of interacting nanostructured surfaces with biomolecular aggregates in a designed manner. Along this line of thinking, we report on a preliminary atomic force microscopy (AFM) investigation of the behavior of F-actin on unstructured surfaces (mica, silicon) and nanostructured surface (13 nm height nanostructured silicon surface).

Original languageEnglish
Title of host publicationNanoscale Imaging, Sensing, and Actuation for Biomedical Applications VI
DOIs
Publication statusPublished - 16 Feb 2009
EventNanoscale Imaging, Sensing, and Actuation for Biomedical Applications VI - San Jose, CA, United States
Duration: 27 Jan 200928 Jan 2009

Publication series

NameProgress in Biomedical Optics and Imaging - Proceedings of SPIE
Volume7188
ISSN (Print)1605-7422

Conference

ConferenceNanoscale Imaging, Sensing, and Actuation for Biomedical Applications VI
Country/TerritoryUnited States
CitySan Jose, CA
Period27/01/0928/01/09

Keywords

  • Actin
  • Atomic force microscopy
  • Nanostructures
  • Self-assembly

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