Management of the neck and regional recurrence in squamous cell carcinoma of the maxillary alveolus and hard palate compared with other sites in the oral cavity

J S Brown, F Bekiroglu, R J Shaw, J A Woolgar, Simon N Rogers

Research output: Contribution to journalArticle

21 Citations (Scopus)

Abstract

Background: The aim of this article was to assess the management of the neck and regional recurrence for squamous cell carcinoma of the maxillary alveolus and hard palate (n = 43) and compare that to the rest of the oral cancer sites (n = 465). Methods: This is a retrospective report through database and case note review. Results: The incidence of nodal metastases (pathologic node–positive necks added to regional recurrence for clinical N0 and pathologic N0) was 37% (16/43) for maxillary alveolus and hard palate compared with 40% (187/465) for the oral cavity in general. Regional recurrence occurred in 26% (11/43) in the maxillary alveolus and hard palate compared with 7% (31/465) in the remaining oral cavity sites (p = .001). Conclusions: Squamous cell carcinoma arising in the maxillary alveolus and hard palate has a similar risk of regional metastasis as the rest of the oral cavity, and a lower propensity for selective neck dissection is resulting in higher regional recurrence and lower survival rates.
Original languageEnglish
JournalHead & Neck
DOIs
Publication statusPublished - 6 Feb 2012

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Hard Palate
Mouth
Squamous Cell Carcinoma
Neck
Recurrence
Neoplasm Metastasis
Neck Dissection
Mouth Neoplasms
Databases
Incidence

Cite this

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title = "Management of the neck and regional recurrence in squamous cell carcinoma of the maxillary alveolus and hard palate compared with other sites in the oral cavity",
abstract = "Background: The aim of this article was to assess the management of the neck and regional recurrence for squamous cell carcinoma of the maxillary alveolus and hard palate (n = 43) and compare that to the rest of the oral cancer sites (n = 465). Methods: This is a retrospective report through database and case note review. Results: The incidence of nodal metastases (pathologic node–positive necks added to regional recurrence for clinical N0 and pathologic N0) was 37{\%} (16/43) for maxillary alveolus and hard palate compared with 40{\%} (187/465) for the oral cavity in general. Regional recurrence occurred in 26{\%} (11/43) in the maxillary alveolus and hard palate compared with 7{\%} (31/465) in the remaining oral cavity sites (p = .001). Conclusions: Squamous cell carcinoma arising in the maxillary alveolus and hard palate has a similar risk of regional metastasis as the rest of the oral cavity, and a lower propensity for selective neck dissection is resulting in higher regional recurrence and lower survival rates.",
author = "Brown, {J S} and F Bekiroglu and Shaw, {R J} and Woolgar, {J A} and Rogers, {Simon N}",
year = "2012",
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doi = "10.1002/hed.22957",
language = "English",
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Management of the neck and regional recurrence in squamous cell carcinoma of the maxillary alveolus and hard palate compared with other sites in the oral cavity. / Brown, J S; Bekiroglu, F; Shaw, R J; Woolgar, J A; Rogers, Simon N.

In: Head & Neck, 06.02.2012.

Research output: Contribution to journalArticle

TY - JOUR

T1 - Management of the neck and regional recurrence in squamous cell carcinoma of the maxillary alveolus and hard palate compared with other sites in the oral cavity

AU - Brown, J S

AU - Bekiroglu, F

AU - Shaw, R J

AU - Woolgar, J A

AU - Rogers, Simon N

PY - 2012/2/6

Y1 - 2012/2/6

N2 - Background: The aim of this article was to assess the management of the neck and regional recurrence for squamous cell carcinoma of the maxillary alveolus and hard palate (n = 43) and compare that to the rest of the oral cancer sites (n = 465). Methods: This is a retrospective report through database and case note review. Results: The incidence of nodal metastases (pathologic node–positive necks added to regional recurrence for clinical N0 and pathologic N0) was 37% (16/43) for maxillary alveolus and hard palate compared with 40% (187/465) for the oral cavity in general. Regional recurrence occurred in 26% (11/43) in the maxillary alveolus and hard palate compared with 7% (31/465) in the remaining oral cavity sites (p = .001). Conclusions: Squamous cell carcinoma arising in the maxillary alveolus and hard palate has a similar risk of regional metastasis as the rest of the oral cavity, and a lower propensity for selective neck dissection is resulting in higher regional recurrence and lower survival rates.

AB - Background: The aim of this article was to assess the management of the neck and regional recurrence for squamous cell carcinoma of the maxillary alveolus and hard palate (n = 43) and compare that to the rest of the oral cancer sites (n = 465). Methods: This is a retrospective report through database and case note review. Results: The incidence of nodal metastases (pathologic node–positive necks added to regional recurrence for clinical N0 and pathologic N0) was 37% (16/43) for maxillary alveolus and hard palate compared with 40% (187/465) for the oral cavity in general. Regional recurrence occurred in 26% (11/43) in the maxillary alveolus and hard palate compared with 7% (31/465) in the remaining oral cavity sites (p = .001). Conclusions: Squamous cell carcinoma arising in the maxillary alveolus and hard palate has a similar risk of regional metastasis as the rest of the oral cavity, and a lower propensity for selective neck dissection is resulting in higher regional recurrence and lower survival rates.

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JO - Head and Neck

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SN - 1043-3074

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