Inducible heat shock protein 70 and its role in preconditioning and exercise

Leigh A. Madden, Marie E. Sandström, Ric J. Lovell, Lars McNaughton

Research output: Contribution to journalArticle

49 Citations (Scopus)

Abstract

Heat shock proteins (Hsp) are well known to be expressed in response to a range of cellular stresses. They are known to convey protection against protein denaturation and a subsequent immediate stress. Inducible heat shock protein 70 (Hsp70) is among the most studied of these stress proteins and its role and function are discussed here in terms of thermal and in particular exercise preconditioning. Preconditioning has been shown to confer cellular protection via expression Hsp, which may be of benefit in preventing protein damage following subsequent periods of exercise. Many studies have used animal models to gather data on Hsp70 and these and the most recent human studies are discussed.
Original languageEnglish
Pages (from-to)511-516
Number of pages6
JournalAmino Acids
Volume34
Issue number4
DOIs
Publication statusPublished - May 2008

Fingerprint

HSP70 Heat-Shock Proteins
Heat-Shock Proteins
Protein Denaturation
Denaturation
Animals
Proteins
Animal Models
Hot Temperature

Keywords

  • Exercise
  • Hsp70
  • Thermal preconditioning

Cite this

Madden, Leigh A. ; Sandström, Marie E. ; Lovell, Ric J. ; McNaughton, Lars. / Inducible heat shock protein 70 and its role in preconditioning and exercise. In: Amino Acids. 2008 ; Vol. 34, No. 4. pp. 511-516.
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Inducible heat shock protein 70 and its role in preconditioning and exercise. / Madden, Leigh A.; Sandström, Marie E.; Lovell, Ric J.; McNaughton, Lars.

In: Amino Acids, Vol. 34, No. 4, 05.2008, p. 511-516.

Research output: Contribution to journalArticle

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