Health related quality of life following oral cancer: 10-year outcomes


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    Objective. The aim is to report 10-year health-related quality of life (HRQOL) outcomes following the treatment of oral squamous cell carcinoma (OSCC).
    Study Design. Cross-sectional HRQOL surveys collated over a 13-year period for patients treated from 1992 gave a cohort of 674 patients with OSCC who had undergone treatment with curative intent. HRQOL measured using the UWQOL closest to 2 and 10 years. Results. UWQOL data were available for 67% (154) of 230 patients alive at 10 years. Three-quarters reported their overall QOL as good, very good or outstanding. Free-flap surgery was the strongest predictor of overall QOL being less than good at 10 years. A significant problem or dysfunction was reported by a minority of patients, ranging from 7% to 13% across the 12 UWQOL domains. At the group level the changes from 2 years to 10 years were minimal with some improvement observed in appearance, chewing, mood and anxiety and deterioration in regard to swallowing. There was considerable scatter in individual changes over time.
    Conclusions As a group, HRQOL at 10 years is similar to that at 2 years however at an individual patient level domains were not so stable.
    Original languageEnglish
    JournalOral Surgery, Oral Medicine, Oral Pathology and Oral Radiology
    Early online date31 May 2020
    Publication statusE-pub ahead of print - 31 May 2020


    • oral cancer; mouth neoplasm; squamous cell carcinoma, ten years; long term; health related quality of life; UW-QOL


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