Guard proteins keep watch at epithelial walls

Alejandra Zarate-Potes; Katja Dierking

doi:10.1016/j.immuni.2021.06.004

Guard proteins keep watch at epithelial walls

Alejandra Zarate-Potes
, Katja Dierking

Biology

Lancaster University
Christian-Albrechts University

Research output: Contribution to journal › Article (journal) › peer-review

Abstract

Cells can detect pathogens through guard proteins that sense disturbances in core cellular processes, but the exact mechanisms often remain elusive. In this issue of Immunity, Orzalli et al. identify Bcl-2 family members as guard proteins that detect virus-induced translational inhibition and induce pyroptosis in human keratinocytes.

Original language	English
Pages (from-to)	1366-1368
Number of pages	3
Journal	Immunity
Volume	54
Issue number	7
DOIs	https://doi.org/10.1016/j.immuni.2021.06.004
Publication status	Published - 13 Jul 2021

Keywords

guard proteins
epithelial walls
immunity
molecular perturbations
cellular homeostasis

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10.1016/j.immuni.2021.06.004

Cite this

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title = "Guard proteins keep watch at epithelial walls",

abstract = "Cells can detect pathogens through guard proteins that sense disturbances in core cellular processes, but the exact mechanisms often remain elusive. In this issue of Immunity, Orzalli et al. identify Bcl-2 family members as guard proteins that detect virus-induced translational inhibition and induce pyroptosis in human keratinocytes. ",

keywords = "guard proteins, epithelial walls, immunity, molecular perturbations, cellular homeostasis",

author = "Alejandra Zarate-Potes and Katja Dierking",

note = "Publisher Copyright: {\textcopyright} 2021 Elsevier Inc.",

year = "2021",

month = jul,

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doi = "10.1016/j.immuni.2021.06.004",

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AU - Zarate-Potes, Alejandra

AU - Dierking, Katja

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AB - Cells can detect pathogens through guard proteins that sense disturbances in core cellular processes, but the exact mechanisms often remain elusive. In this issue of Immunity, Orzalli et al. identify Bcl-2 family members as guard proteins that detect virus-induced translational inhibition and induce pyroptosis in human keratinocytes.

KW - guard proteins

KW - epithelial walls

KW - immunity

KW - molecular perturbations

KW - cellular homeostasis

UR - https://puretest.lancaster.ac.uk/portal/en/publications/guard-proteins-keep-watch-at-epithelial-walls(ff60a975-f7b0-4280-879b-2a9b0427a5b8).html

U2 - 10.1016/j.immuni.2021.06.004

DO - 10.1016/j.immuni.2021.06.004

M3 - Article (journal)

SN - 1074-7613

VL - 54

SP - 1366

EP - 1368

JO - Immunity

JF - Immunity

IS - 7

ER -

Guard proteins keep watch at epithelial walls

Abstract

Keywords

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