Abstract
Cells can detect pathogens through guard proteins that sense disturbances in core cellular processes, but the exact mechanisms often remain elusive. In this issue of Immunity, Orzalli et al. identify Bcl-2 family members as guard proteins that detect virus-induced translational inhibition and induce pyroptosis in human keratinocytes.
Original language | English |
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Pages (from-to) | 1-3 |
Number of pages | 3 |
Journal | Immunity |
DOIs | |
Publication status | Published - 13 Jul 2021 |
Keywords
- guard proteins
- epithelial walls
- immunity
- molecular perturbations
- cellular homeostasis