Feasibility of a high-protein Mediterranean-style diet and resistance exercise in cardiac rehabilitation patients with sarcopenic obesity (PRiMER): Study protocol for a randomised control trial.:  Study protocol for a randomised control trial

Deaglan McCullough; Richard Kirwan; Tom Butler; Fatima Perez de Heredia; Dick Thijssen; Gregory Y.H. Lip; Joseph Mills; Ian G. Davies

doi:10.1016/j.clnesp.2021.08.001

Feasibility of a high-protein Mediterranean-style diet and resistance exercise in cardiac rehabilitation patients with sarcopenic obesity (PRiMER): Study protocol for a randomised control trial. Study protocol for a randomised control trial

Deaglan McCullough, Richard Kirwan, Tom Butler, Fatima Perez de Heredia, Dick Thijssen, Gregory Y.H. Lip, Joseph Mills, Ian G. Davies

Allied Health, Social Work & Wellbeing

Research output: Contribution to journal › Article (journal) › peer-review

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Abstract

Cardiac rehabilitation (CR) is an essential component of long-term recovery following a cardiac event. Typical CR may not be optimal for patients presenting with sarcopenic obesity (SO) who present with reduced muscle mass and elevated adipose tissue, and may indicate greater cardiovascular disease (CVD) risk. Resistance exercise and high-protein diets are known to increase muscle mass, while Mediterranean-style diets have been shown to reduce CVD risk. A high-protein Mediterranean-style diet combined with resistance exercise intervention is yet to be trialled in cardiac rehabilitation populations.

Original language	English
Pages (from-to)	492-498
Number of pages	7
Journal	Clinical Nutrition ESPEN
Volume	45
Early online date	15 Aug 2021
DOIs	https://doi.org/10.1016/j.clnesp.2021.08.001
Publication status	Published - 1 Oct 2021

Keywords

Mediterranean diet
Cardiac rehabilitation
high-protein
resistance exercise
sarcopenic obesity
anabolic resistance
cardiovascular disease

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1016/j.clnesp.2021.08.001

Revised_ManuscriptAccepted author manuscript, 106 KBLicence: CC BY-NC-ND

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McCullough, D., Kirwan, R., Butler, T., Heredia, F. P. D., Thijssen, D., Lip, G. Y. H., Mills, J., & Davies, I. G. (2021). Feasibility of a high-protein Mediterranean-style diet and resistance exercise in cardiac rehabilitation patients with sarcopenic obesity (PRiMER): Study protocol for a randomised control trial. Study protocol for a randomised control trial. Clinical Nutrition ESPEN, 45, 492-498. https://doi.org/10.1016/j.clnesp.2021.08.001

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title = "Feasibility of a high-protein Mediterranean-style diet and resistance exercise in cardiac rehabilitation patients with sarcopenic obesity (PRiMER): Study protocol for a randomised control trial.: Study protocol for a randomised control trial",

abstract = "Cardiac rehabilitation (CR) is an essential component of long-term recovery following a cardiac event. Typical CR may not be optimal for patients presenting with sarcopenic obesity (SO) who present with reduced muscle mass and elevated adipose tissue, and may indicate greater cardiovascular disease (CVD) risk. Resistance exercise and high-protein diets are known to increase muscle mass, while Mediterranean-style diets have been shown to reduce CVD risk. A high-protein Mediterranean-style diet combined with resistance exercise intervention is yet to be trialled in cardiac rehabilitation populations.",

keywords = "Mediterranean diet, Cardiac rehabilitation, high-protein, resistance exercise, sarcopenic obesity, anabolic resistance, cardiovascular disease",

author = "Deaglan McCullough and Richard Kirwan and Tom Butler and Heredia, {Fatima Perez de} and Dick Thijssen and Lip, {Gregory Y.H.} and Joseph Mills and Davies, {Ian G.}",

note = "Funding Information: Liverpool Clinical Commissioning Group (LCCG) and Liverpool John Moores University, Institute for Health Research. The role of LCCG is to support the future design of a larger study for subsequent National Institute of Health Research (NIHR) support. Publisher Copyright: {\textcopyright} 2021 European Society for Clinical Nutrition and Metabolism",

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McCullough, D, Kirwan, R, Butler, T, Heredia, FPD, Thijssen, D, Lip, GYH, Mills, J & Davies, IG 2021, 'Feasibility of a high-protein Mediterranean-style diet and resistance exercise in cardiac rehabilitation patients with sarcopenic obesity (PRiMER): Study protocol for a randomised control trial. Study protocol for a randomised control trial', Clinical Nutrition ESPEN, vol. 45, pp. 492-498. https://doi.org/10.1016/j.clnesp.2021.08.001

Feasibility of a high-protein Mediterranean-style diet and resistance exercise in cardiac rehabilitation patients with sarcopenic obesity (PRiMER): Study protocol for a randomised control trial. Study protocol for a randomised control trial. / McCullough, Deaglan; Kirwan, Richard; Butler, Tom et al.
In: Clinical Nutrition ESPEN, Vol. 45, 01.10.2021, p. 492-498.

Research output: Contribution to journal › Article (journal) › peer-review

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AU - Kirwan, Richard

AU - Butler, Tom

AU - Heredia, Fatima Perez de

AU - Thijssen, Dick

AU - Lip, Gregory Y.H.

AU - Mills, Joseph

AU - Davies, Ian G.

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Y1 - 2021/10/1

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AB - Cardiac rehabilitation (CR) is an essential component of long-term recovery following a cardiac event. Typical CR may not be optimal for patients presenting with sarcopenic obesity (SO) who present with reduced muscle mass and elevated adipose tissue, and may indicate greater cardiovascular disease (CVD) risk. Resistance exercise and high-protein diets are known to increase muscle mass, while Mediterranean-style diets have been shown to reduce CVD risk. A high-protein Mediterranean-style diet combined with resistance exercise intervention is yet to be trialled in cardiac rehabilitation populations.

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KW - high-protein

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KW - sarcopenic obesity

KW - anabolic resistance

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McCullough D, Kirwan R, Butler T, Heredia FPD, Thijssen D, Lip GYH et al. Feasibility of a high-protein Mediterranean-style diet and resistance exercise in cardiac rehabilitation patients with sarcopenic obesity (PRiMER): Study protocol for a randomised control trial. Study protocol for a randomised control trial. Clinical Nutrition ESPEN. 2021 Oct 1;45:492-498. Epub 2021 Aug 15. doi: 10.1016/j.clnesp.2021.08.001