Even experts cannot agree on the optimal use of platelet-rich plasma in lateral elbow tendinopathy: an international Delphi study

Jonathan P. Evans*, Nicola Maffulli, Chris Smith, Adam Watts, Jose Valderas, Vicki Goodwin

*Corresponding author for this work

Research output: Contribution to journalArticle (journal)peer-review

4 Citations (Scopus)

Abstract

Background: Platelet-rich plasma (PRP) is widely used in the management of lateral elbow tendinopathy (LET) despite conflicting evidence on its effectiveness. With high levels of user experience, this study aimed to assess consensus amongst experts on its clinical use. Methods: A three-round international Delphi study was conducted. Participants were invited through national society mailing lists and contact lists derived from a systematic search of the literature on PRP. In round one, a primary working group developed 40 statements on PRP preparation and clinical application. In rounds two and three, an international group of researchers on PRP and clinical users of the device scored their levels of agreement with the statements on a five-point scale. Consensus was defined as an interquartile range of ≤ 1. Results: Consensus of agreement was only reached for 17/40 (42.5%) statements. For statements on PRP formulation, consensus of agreement was reached in 2/6 statements (33%). Only limited consensus on the contraindications, delivery strategy and delivery technique was achieved. Conclusion: Experts reached very limited consensus on the use of PRP in LET. High levels of user experience have not resulted in a convergence of opinion on the technical components of PRP formulation and delivery, substantiating the need for further studies and improved trial reporting.

Original languageEnglish
Article number47
Pages (from-to)47
JournalJournal of Orthopaedics and Traumatology
Volume22
Issue number1
Early online date25 Nov 2021
DOIs
Publication statusPublished - 25 Nov 2021

Keywords

  • Delphi Technique
  • Elbow Tendinopathy
  • Humans
  • Musculoskeletal Diseases
  • Platelet-Rich Plasma
  • Tendinopathy/therapy

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