Evaluation of Post-hoc Interpretability Methods in Breast Cancer Histopathological Image Classification

Muhammad Waqas*, Tomas Maul, Amr Ahmed, Iman Yi Liao

*Corresponding author for this work

Research output: Chapter in Book/Report/Conference proceedingConference proceeding (ISBN)peer-review

1 Citation (Scopus)

Abstract

Methods for post-hoc interpretability are essential for understanding neural network results. Recent years have seen the emergence of numerous post-hoc techniques, but their application to certain tasks, such as histopathological image classification for breast cancer, can produce varied and unpredictable outcomes. Frameworks for quantitative assessment are essential for evaluating each method’s effectiveness. The implementation of post-hoc interpretability methodologies is however hampered by the shortcomings of current frameworks, particularly in high-risk industries. In this study, the performance levels of several common post-hoc interpretability methods are systematically evaluated and compared in the context of histopathological image classification for breast cancer. The study is based on six post-hoc interpretability methods, 3 datasets, and 3 deep neural network models, compared via a RemOve And Retrain (ROAR) approach. The results show that Shapley value sampling obtains the best overall performance in the context of the chosen breast cancer histopathological image datasets.

Original languageEnglish
Title of host publicationAdvances in Brain Inspired Cognitive Systems - 13th International Conference, BICS 2023, Proceedings
EditorsJinchang Ren, Amir Hussain, Iman Yi Liao, Rongjun Chen, Kaizhu Huang, Huimin Zhao, Xiaoyong Liu, Ping Ma, Thomas Maul
PublisherSpringer Science and Business Media Deutschland GmbH
Pages95-104
Number of pages10
ISBN (Print)9789819714162
DOIs
Publication statusPublished - 22 May 2024
Event13th International Conference on Brain Inspired Cognitive Systems, BICS 2023 - Kuala Lumpur, Malaysia
Duration: 5 Aug 20236 Aug 2023

Publication series

NameLecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics)
Volume14374 LNAI
ISSN (Print)0302-9743
ISSN (Electronic)1611-3349

Conference

Conference13th International Conference on Brain Inspired Cognitive Systems, BICS 2023
Country/TerritoryMalaysia
CityKuala Lumpur
Period5/08/236/08/23

Keywords

  • Breast cancer
  • Histopathological images
  • Post-hoc interpretability
  • ROAR

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