Development of an oral regimen of unithiol for the treatment of snakebite envenoming: a phase 1 open-label dose-escalation safety trial and pharmacokinetic analysis in healthy Kenyan adults
- Michael Abouyannis*
- , Yvonne K. Nyambura
- , Samson Ngome
- , Debra Riako
- , Jennifer Musyoki
- , Charles Muiruri
- , Benedict Orindi
- , Laura Else
- , Alieu Amara
- , Laura Dickinson
- , Rachel H. Clare
- , Laura Oana Albulescu
- , Adam P. Westhorpe
- , Jeroen Kool
- , Ifedayo Adetifa
- , Francis M. Ndungu
- , Richard FitzGerald
- , Saye Khoo
- , David G. Lalloo
- , Nicholas R. Casewell
*Corresponding author for this work
- Liverpool School of Tropical Medicine
- KEMRI-Wellcome Research Programme
- University of Liverpool
- Centre for Snakebite Research & Interventions
- Vrije Universiteit Amsterdam
- Centre for Analytical Sciences Amsterdam
- London School of Hygiene and Tropical Medicine
- Liverpool University Hospitals NHS Foundation Trust
- University of Oxford
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