Cystatin M/E Variant Causes Autosomal Dominant Keratosis Follicularis Spinulosa Decalvans by Dysregulating Cathepsins L and V

Medicine & Life Sciences

• X-Linked Keratosis Follicularis Spinulosa Decalvans 100%
• Cystatin M 98%
• Cathepsin L 70%
• transglutaminase 1 42%
• Nuclear Family 27%
• Keratinocytes 24%
• Sterol Regulatory Element Binding Proteins 19%
• Parents 18%
• Cysteine Proteinase Inhibitors 17%
• Cathepsins 16%
• Transglutaminases 16%
• X-Linked Genes 16%
• Gene Expression 15%
• Whole Exome Sequencing 14%
• Metalloproteases 13%
• Hair 12%
• Zinc 12%
• Peptide Hydrolases 10%
• Mothers 8%
• Autosomal Dominant Keratosis Follicularis Spinulosa Decalvans 7%
• Phenotype 7%
• Membranes 7%
• Mutation 7%
• DNA 7%
• Genes 5%
• Proteins 4%