Abstract
Obesity and type 2 diabetes mellitus are the most frequent nutritional disorders found in the
developed countries and are associated with a high cardiovascular mortality and morbidity. They are
multifactorial associations and nutritional disorders, resulting from a genetic component and a
multitude of environmental factors. The clinical observation determined the association of the obesity
and diabetes mellitus with high blood pressure, dislipidemia and atherosclerosis. These conditions
represent a public health problem, due to the high prevalence and its association with high risk
cardiovascular diseases; both conditions have a high incidence in developed countries. Visfatin is an
adipocytokine identified in 2005, its name suggesting the idea that it is predominantly produced in the
visceral fat. It has a molecular weight of 52 kDa and it has in its structure, 491 aminoacid residues. It
is identical to the PBEF, that was described in 1994 as a lymphocytes produced cytokine.
developed countries and are associated with a high cardiovascular mortality and morbidity. They are
multifactorial associations and nutritional disorders, resulting from a genetic component and a
multitude of environmental factors. The clinical observation determined the association of the obesity
and diabetes mellitus with high blood pressure, dislipidemia and atherosclerosis. These conditions
represent a public health problem, due to the high prevalence and its association with high risk
cardiovascular diseases; both conditions have a high incidence in developed countries. Visfatin is an
adipocytokine identified in 2005, its name suggesting the idea that it is predominantly produced in the
visceral fat. It has a molecular weight of 52 kDa and it has in its structure, 491 aminoacid residues. It
is identical to the PBEF, that was described in 1994 as a lymphocytes produced cytokine.
Original language | English |
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Pages (from-to) | 37-43 |
Number of pages | 7 |
Journal | Proceedings of the Romanian Academy Series B: Chemistry, Life Sciences and Geoscience |
Volume | 14 |
Issue number | 1 |
Publication status | Published - 12 Dec 2011 |
Externally published | Yes |
Keywords
- visfatin
- diabetes mellitus
- cholesterol
- obesity
- LDL
- HDL