Contextual factors associated with subjective effects of cannabis: A systematic review and meta-analysis

Research output: Contribution to journalArticle (journal)peer-review

Abstract

Background: Cannabis is consumed in various social and environmental settings, and such contexts may be important predictors of subjective effects. The aim of this systematic review and meta-analysis was to examine the relationship between contextual factors and subjective effects of cannabis.
Methods: A PRISMA-guided search of MEDLINE, Embase, PsycINFO, Global Health, and Google Scholar yielded 29 studies.
Results: Study type (Ecological Momentary Assessment or Experimental) was a significant predictor of intoxication effects, and experimental studies had a greater pooled effect size (z = .296,95% CI [.132,.478], p= .004) than Ecological Momentary Assessment (EMA) studies (z = .071,95% CI [.011,.130], p = .02). Contextual conditions (environment, social group, expectancy, time of day, day of week) were not significant predictors of cannabis effects.
Conclusion: Findings did not point to a significant association between contextual conditions and subjective effects. However, as current literature is methodologically weak, it may be premature to conclude that subjective effects are not shaped at all by contextual factors. In view of policy and therapeutic implications, replications and study refinements are recommended.
Original languageEnglish
Article number105822
JournalNeuroscience and Biobehavioral Reviews
Volume164
Early online date25 Jul 2024
DOIs
Publication statusPublished - 30 Sept 2024

Keywords

  • Cannabis use
  • Subjective effects
  • Intoxication
  • Context
  • Contextual factors
  • Settings
  • Substance Use
  • Meta-analysis
  • Systematic review
  • Substance use

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