Arterial stiffness is an emerging risk factor for cardiovascular disease (CVD), and dietary polyphenols, particularly anthocyanins, may play an important role in mediating vascular tone. The present single-blind randomised cross-over placebo controlled study investigated the effect of consumption of an anthocyanin-rich potato, Purple Majesty (PM) in 14 healthy male and female adults. Participants consumed 200 g of cooked PM containing 114 mg anthocyanins, or placebo (Osprey) with negligible anthocyanin content for 14 days, separated by a 1-week washout period. Non-invasive assessment of vascular tone (arterial stiffness) by pulse wave velocity (PWV) was determined in addition to systolic (SBP) and diastolic blood pressure (DBP), high density lipoproteins (HDL), low-density lipoproteins (LDL), triglycerides, glucose, insulin resistance (HOMA-IR) and c-reactive protein (CRP). Arterial stiffness was significantly reduced (p=0.001) following PM consumption. There were no significant changes with any other clinical parameter measured, and no changes were observed following placebo. PM contained higher levels of total phenolics, total anthocyanins and antioxidant capacity and daily consumption of PM over 14 days was well tolerated by participants. The findings from this study suggest improved vascular tone following daily consumption of PM and inclusion in the diet could provide a rich and valuable source of anthocyanins.
|Publication status||E-pub ahead of print - 6 Nov 2017|
|Event||2nd International Conference on Obesity - Barcelona, Spain|
Duration: 6 Nov 2017 → 8 Nov 2017
|Conference||2nd International Conference on Obesity|
|Period||6/11/17 → 8/11/17|
- Arterial Stiffness
- Pulse wave velocity