AMD-associated cystatin C variant impacts RPE differentiation and mitochondrial activity

Ioan Valentin Matei; Tanachapa Jantalika; DANIEL GRIMES; LUMINITA PARAOAN

AMD-associated cystatin C variant impacts RPE differentiation and mitochondrial activity

Ioan Valentin Matei, Tanachapa Jantalika, DANIEL GRIMES, LUMINITA PARAOAN^*

^*Corresponding author for this work

Biology

Division of Cell Biology, Department of Preclinical Sciences, Thammasat University Faculty of Medicine, Pathumthani, Thailand

Research output: Contribution to journal › Conference proceeding article (ISSN) › peer-review

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Original language	English
Article number	1324
Journal	Investigative Ophthalmology & Visual Science
Volume	65
Issue number	7
Publication status	Published - 1 Jul 2024
Event	ARVO Annual Meeting 2024 - Seattle, United States Duration: 5 May 2024 → 9 May 2024 https://www.arvo.org/

Keywords

AMD-associated variant B cystatin C (var B CysC)
Intracellular trafficking
Mitochondrial association
Differentiation
Mitochondrial activity
ARPE-19 cells
TER (Trans-epithelial electrical resistance)
Functional RPE genes (CST3, BEST1, CRALBP, RDH5, LRAT)
Mitochondrial dynamics/mitophagy markers (MFN1, MFN2, OPA1, DRP1, PINK1, SPPL2B)
PARK2
LC3B
TMRE (Tetramethylrhodamine ethyl ester)
MitoTracker
ROS (Reactive oxygen species)
SOX (Superoxide) production

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AMD-associated cystatin C variant impacts RPE differentiation and mitochondrial activityAccepted author manuscript, 135 KBLicence: CC BY-NC-ND

https://iovs.arvojournals.org/article.aspx?articleid=2796853&resultClick=1Licence: CC BY-NC-ND

Cite this

@article{06de328451c34d089db6f7bd04031036,

title = "AMD-associated cystatin C variant impacts RPE differentiation and mitochondrial activity",

keywords = "AMD-associated variant B cystatin C (var B CysC), Intracellular trafficking, Mitochondrial association, Differentiation, Mitochondrial activity, ARPE-19 cells, TER (Trans-epithelial electrical resistance), Functional RPE genes (CST3, BEST1, CRALBP, RDH5, LRAT), Mitochondrial dynamics/mitophagy markers (MFN1, MFN2, OPA1, DRP1, PINK1, SPPL2B), PARK2, LC3B, TMRE (Tetramethylrhodamine ethyl ester), MitoTracker, ROS (Reactive oxygen species), SOX (Superoxide) production",

author = "Matei, {Ioan Valentin} and Tanachapa Jantalika and DANIEL GRIMES and LUMINITA PARAOAN",

year = "2024",

month = jul,

day = "1",

language = "English",

volume = "65",

journal = "Investigative Ophthalmology & Visual Science",

issn = "1552-5783",

publisher = "ARVO",

number = "7",

note = "ARVO Annual Meeting 2024 ; Conference date: 05-05-2024 Through 09-05-2024",

url = "https://www.arvo.org/",

}

TY - JOUR

T1 - AMD-associated cystatin C variant impacts RPE differentiation and mitochondrial activity

AU - Matei, Ioan Valentin

AU - Jantalika, Tanachapa

AU - GRIMES, DANIEL

AU - PARAOAN, LUMINITA

PY - 2024/7/1

Y1 - 2024/7/1

KW - AMD-associated variant B cystatin C (var B CysC)

KW - Intracellular trafficking

KW - Mitochondrial association

KW - Differentiation

KW - Mitochondrial activity

KW - ARPE-19 cells

KW - TER (Trans-epithelial electrical resistance)

KW - Functional RPE genes (CST3, BEST1, CRALBP, RDH5, LRAT)

KW - Mitochondrial dynamics/mitophagy markers (MFN1, MFN2, OPA1, DRP1, PINK1, SPPL2B)

KW - PARK2

KW - LC3B

KW - TMRE (Tetramethylrhodamine ethyl ester)

KW - MitoTracker

KW - ROS (Reactive oxygen species)

KW - SOX (Superoxide) production

M3 - Conference proceeding article (ISSN)

SN - 1552-5783

VL - 65

JO - Investigative Ophthalmology & Visual Science

JF - Investigative Ophthalmology & Visual Science

IS - 7

M1 - 1324

T2 - ARVO Annual Meeting 2024

Y2 - 5 May 2024 through 9 May 2024

ER -