Alterations in the myocardial ceramide pool following dietary intervention in an experimental model of cardiac hypertrophy

THOMAS BUTLER; Anne-Marie Seymour; David Ashford

doi:10.1093/cvr/cvr336

Alterations in the myocardial ceramide pool following dietary intervention in an experimental model of cardiac hypertrophy

THOMAS BUTLER^*, Anne-Marie Seymour, David Ashford

^*Corresponding author for this work

Research output: Contribution to journal › Article (journal) › peer-review

Abstract

Fibroblast growth factors (FGFs) and their receptors play an important role during embryonic induction and patterning, as well as in modulating proliferative and hypertrophic growth in fetal and adult organs. Exogenous FGF2 (also known as basic FGF) was found to be able to induce proliferation of chick embryonic and fetal cardiac myocytes in vivo and is also important for vascular development.

The aim of this study was to assess the effect of FGF2 signaling on growth of chick embryonic ventricular wall and its vascularization

Original language	English
Article number	P492
Pages (from-to)	4
Number of pages	4
Journal	Cardiovascular Research
DOIs	https://doi.org/10.1093/cvr/cvr336
Publication status	Published - 15 Mar 2012
Externally published	Yes

Keywords

ceramide
left ventricular hypertrophy
western diet

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10.1093/cvr/cvr336

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title = "Alterations in the myocardial ceramide pool following dietary intervention in an experimental model of cardiac hypertrophy",

abstract = "Fibroblast growth factors (FGFs) and their receptors play an important role during embryonic induction and patterning, as well as in modulating proliferative and hypertrophic growth in fetal and adult organs. Exogenous FGF2 (also known as basic FGF) was found to be able to induce proliferation of chick embryonic and fetal cardiac myocytes in vivo and is also important for vascular development.The aim of this study was to assess the effect of FGF2 signaling on growth of chick embryonic ventricular wall and its vascularization",

keywords = "ceramide, left ventricular hypertrophy, western diet",

author = "THOMAS BUTLER and Anne-Marie Seymour and David Ashford",

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doi = "10.1093/cvr/cvr336",

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journal = "Cardiovascular Research",

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T1 - Alterations in the myocardial ceramide pool following dietary intervention in an experimental model of cardiac hypertrophy

AU - BUTLER, THOMAS

AU - Seymour, Anne-Marie

AU - Ashford, David

PY - 2012/3/15

Y1 - 2012/3/15

N2 - Fibroblast growth factors (FGFs) and their receptors play an important role during embryonic induction and patterning, as well as in modulating proliferative and hypertrophic growth in fetal and adult organs. Exogenous FGF2 (also known as basic FGF) was found to be able to induce proliferation of chick embryonic and fetal cardiac myocytes in vivo and is also important for vascular development.The aim of this study was to assess the effect of FGF2 signaling on growth of chick embryonic ventricular wall and its vascularization

AB - Fibroblast growth factors (FGFs) and their receptors play an important role during embryonic induction and patterning, as well as in modulating proliferative and hypertrophic growth in fetal and adult organs. Exogenous FGF2 (also known as basic FGF) was found to be able to induce proliferation of chick embryonic and fetal cardiac myocytes in vivo and is also important for vascular development.The aim of this study was to assess the effect of FGF2 signaling on growth of chick embryonic ventricular wall and its vascularization

KW - ceramide

KW - left ventricular hypertrophy

KW - western diet

UR - https://doi.org/10.1093/cvr/cvr336

U2 - 10.1093/cvr/cvr336

DO - 10.1093/cvr/cvr336

M3 - Article (journal)

SN - 0008-6363

SP - 4

JO - Cardiovascular Research

JF - Cardiovascular Research

M1 - P492

ER -

Alterations in the myocardial ceramide pool following dietary intervention in an experimental model of cardiac hypertrophy

Abstract

Keywords

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