Alterations in the myocardial ceramide pool following dietary intervention in an experimental model of cardiac hypertrophy

THOMAS BUTLER*, Anne-Marie Seymour, David Ashford

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

Abstract

Fibroblast growth factors (FGFs) and their receptors play an important role during embryonic induction and patterning, as well as in modulating proliferative and hypertrophic growth in fetal and adult organs. Exogenous FGF2 (also known as basic FGF) was found to be able to induce proliferation of chick embryonic and fetal cardiac myocytes in vivo and is also important for vascular development.

The aim of this study was to assess the effect of FGF2 signaling on growth of chick embryonic ventricular wall and its vascularization
Original languageEnglish
Article numberP492
Pages (from-to)4
Number of pages4
JournalCardiovascular Research
DOIs
Publication statusPublished - 15 Mar 2012
Externally publishedYes

Keywords

  • ceramide
  • left ventricular hypertrophy
  • western diet

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