A novel method for the detection of transient myocardial ischaemia using body suface electrocardiac mapping.

Simon Carley, Kevin Mackway-Jones, Michelle Jenkins, E. Darlington, F. Fath-Ordoubadi, N. Curzen

    Research output: Contribution to journalArticle

    10 Citations (Scopus)

    Abstract

    Background: The limitations of the 12-lead ECG in the detection of myocardial ischaemia are well known. This study sought to test the hypothesis that a Body Surface Mapping (BSM) system can detect and localise the transient regional ischaemia induced by elective percutaneous coronary intervention (PCI) in patients with stable angina. Methods and Results: 25 patients undergoing elective single vessel PCI were studied: 11 with RCA lesions, 9 with LAD lesions and 5 with circumflex lesions. Patients had BSM readings every 30 s following the inflation of a dilating balloon in the target vessel for 1 min. BSMs were analysed for ST segment change at 60 ms after the J point (ST60). Peak ST changes were analysed and colour map reconstruction made. Characteristic ST segment changes in each arterial domain were observed following inflation of the balloon. Maximal change occurred in a standard V lead on only 2/46 occasions. Statistically significant rapid rise and fall of ST 60 readings were observed indicating the onset recovery and location of the transient ischaemia. A novel method for the presentation of colour map reconstruction that removes baseline noise has been developed. Conclusions: These data confirm the hypothesis that this BSM system can detect and display transient myocardial ischaemia. BSM may represent a novel clinical tool for the assessment of clinical ischaemia.
    Original languageEnglish
    Pages (from-to)75-81
    JournalInternational Journal of Cardiology
    Volume95
    Publication statusPublished - 2004

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    Body Surface Potential Mapping
    Myocardial Ischemia
    Ischemia
    Economic Inflation
    Percutaneous Coronary Intervention
    Reading
    Color
    Stable Angina
    Noise
    Electrocardiography

    Cite this

    Carley, S., Mackway-Jones, K., Jenkins, M., Darlington, E., Fath-Ordoubadi, F., & Curzen, N. (2004). A novel method for the detection of transient myocardial ischaemia using body suface electrocardiac mapping. International Journal of Cardiology, 95, 75-81.
    Carley, Simon ; Mackway-Jones, Kevin ; Jenkins, Michelle ; Darlington, E. ; Fath-Ordoubadi, F. ; Curzen, N. / A novel method for the detection of transient myocardial ischaemia using body suface electrocardiac mapping. In: International Journal of Cardiology. 2004 ; Vol. 95. pp. 75-81.
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    title = "A novel method for the detection of transient myocardial ischaemia using body suface electrocardiac mapping.",
    abstract = "Background: The limitations of the 12-lead ECG in the detection of myocardial ischaemia are well known. This study sought to test the hypothesis that a Body Surface Mapping (BSM) system can detect and localise the transient regional ischaemia induced by elective percutaneous coronary intervention (PCI) in patients with stable angina. Methods and Results: 25 patients undergoing elective single vessel PCI were studied: 11 with RCA lesions, 9 with LAD lesions and 5 with circumflex lesions. Patients had BSM readings every 30 s following the inflation of a dilating balloon in the target vessel for 1 min. BSMs were analysed for ST segment change at 60 ms after the J point (ST60). Peak ST changes were analysed and colour map reconstruction made. Characteristic ST segment changes in each arterial domain were observed following inflation of the balloon. Maximal change occurred in a standard V lead on only 2/46 occasions. Statistically significant rapid rise and fall of ST 60 readings were observed indicating the onset recovery and location of the transient ischaemia. A novel method for the presentation of colour map reconstruction that removes baseline noise has been developed. Conclusions: These data confirm the hypothesis that this BSM system can detect and display transient myocardial ischaemia. BSM may represent a novel clinical tool for the assessment of clinical ischaemia.",
    author = "Simon Carley and Kevin Mackway-Jones and Michelle Jenkins and E. Darlington and F. Fath-Ordoubadi and N. Curzen",
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    Carley, S, Mackway-Jones, K, Jenkins, M, Darlington, E, Fath-Ordoubadi, F & Curzen, N 2004, 'A novel method for the detection of transient myocardial ischaemia using body suface electrocardiac mapping.', International Journal of Cardiology, vol. 95, pp. 75-81.

    A novel method for the detection of transient myocardial ischaemia using body suface electrocardiac mapping. / Carley, Simon; Mackway-Jones, Kevin; Jenkins, Michelle; Darlington, E.; Fath-Ordoubadi, F.; Curzen, N.

    In: International Journal of Cardiology, Vol. 95, 2004, p. 75-81.

    Research output: Contribution to journalArticle

    TY - JOUR

    T1 - A novel method for the detection of transient myocardial ischaemia using body suface electrocardiac mapping.

    AU - Carley, Simon

    AU - Mackway-Jones, Kevin

    AU - Jenkins, Michelle

    AU - Darlington, E.

    AU - Fath-Ordoubadi, F.

    AU - Curzen, N.

    PY - 2004

    Y1 - 2004

    N2 - Background: The limitations of the 12-lead ECG in the detection of myocardial ischaemia are well known. This study sought to test the hypothesis that a Body Surface Mapping (BSM) system can detect and localise the transient regional ischaemia induced by elective percutaneous coronary intervention (PCI) in patients with stable angina. Methods and Results: 25 patients undergoing elective single vessel PCI were studied: 11 with RCA lesions, 9 with LAD lesions and 5 with circumflex lesions. Patients had BSM readings every 30 s following the inflation of a dilating balloon in the target vessel for 1 min. BSMs were analysed for ST segment change at 60 ms after the J point (ST60). Peak ST changes were analysed and colour map reconstruction made. Characteristic ST segment changes in each arterial domain were observed following inflation of the balloon. Maximal change occurred in a standard V lead on only 2/46 occasions. Statistically significant rapid rise and fall of ST 60 readings were observed indicating the onset recovery and location of the transient ischaemia. A novel method for the presentation of colour map reconstruction that removes baseline noise has been developed. Conclusions: These data confirm the hypothesis that this BSM system can detect and display transient myocardial ischaemia. BSM may represent a novel clinical tool for the assessment of clinical ischaemia.

    AB - Background: The limitations of the 12-lead ECG in the detection of myocardial ischaemia are well known. This study sought to test the hypothesis that a Body Surface Mapping (BSM) system can detect and localise the transient regional ischaemia induced by elective percutaneous coronary intervention (PCI) in patients with stable angina. Methods and Results: 25 patients undergoing elective single vessel PCI were studied: 11 with RCA lesions, 9 with LAD lesions and 5 with circumflex lesions. Patients had BSM readings every 30 s following the inflation of a dilating balloon in the target vessel for 1 min. BSMs were analysed for ST segment change at 60 ms after the J point (ST60). Peak ST changes were analysed and colour map reconstruction made. Characteristic ST segment changes in each arterial domain were observed following inflation of the balloon. Maximal change occurred in a standard V lead on only 2/46 occasions. Statistically significant rapid rise and fall of ST 60 readings were observed indicating the onset recovery and location of the transient ischaemia. A novel method for the presentation of colour map reconstruction that removes baseline noise has been developed. Conclusions: These data confirm the hypothesis that this BSM system can detect and display transient myocardial ischaemia. BSM may represent a novel clinical tool for the assessment of clinical ischaemia.

    UR - http://www.sciencedirect.com/science/article/pii/S0167527303003760

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    Carley S, Mackway-Jones K, Jenkins M, Darlington E, Fath-Ordoubadi F, Curzen N. A novel method for the detection of transient myocardial ischaemia using body suface electrocardiac mapping. International Journal of Cardiology. 2004;95:75-81.