A meta-analysis of cumin (Cuminum cyminim L.) consumption on metabolic and anthropometric indices in overweight and type 2 diabetics

Sadegh Jafarnejad, Catherine Tsang, Moshen Taghizadeh, Asemi Zatollah, Seyed Ali Keshavarz

Research output: Contribution to journalArticle (journal)peer-review

28 Citations (Scopus)
112 Downloads (Pure)

Abstract

Objective To conduct a systematic review, including meta-analysis, of published randomised controlled trials (RCTs) of cumin to determine the effect on anthropometric and metabolic indices in overweight and/or type 2 diabetics, relative to controls. Methods Studies were identified by a search of electronic databases before December 2017. Combined and stratified analyses were used. Results Seven trials were identified, and data from 412 subjects were included. Pooled analysis showed improvements in bodyweight, body mass index (BMI) and fasting blood glucose (FBG) by −1.74 kg, −0.67 kg/m2 and −17.82 mg/dL respectively. Significant findings were also observed in triglycerides (TG) [WMD: −21.23 (95% CI: −37.64 to −4.82; P < 0.001, I2 = 92%)] and HDL-c (high-density lipoprotein cholesterol) [WMD: 4.16 (95%CI: 3.30, 5.01; P < 0.001, I2 = 82%)] following cumin intake. No changes were found in controls. Conclusions Cumin improves anthropometric and metabolic indices in overweight and/or type 2 diabetic subjects. The changes were related to the clinical condition and quality assessment.
Original languageEnglish
Pages (from-to)313-321
JournalJournal of Functional Foods
Volume44
Early online date23 Mar 2018
DOIs
Publication statusE-pub ahead of print - 23 Mar 2018

Keywords

  • Cumin
  • Anthropometrics
  • Glycaemic status
  • Lipid profile
  • Type 2 diabetes
  • Overweight

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