Abstract
Objective
To conduct a systematic review, including meta-analysis, of published randomised controlled trials (RCTs) of cumin to determine the effect on anthropometric and metabolic indices in overweight and/or type 2 diabetics, relative to controls.
Methods
Studies were identified by a search of electronic databases before December 2017. Combined and stratified analyses were used.
Results
Seven trials were identified, and data from 412 subjects were included. Pooled analysis showed improvements in bodyweight, body mass index (BMI) and fasting blood glucose (FBG) by −1.74 kg, −0.67 kg/m2 and −17.82 mg/dL respectively. Significant findings were also observed in triglycerides (TG) [WMD: −21.23 (95% CI: −37.64 to −4.82; P < 0.001, I2 = 92%)] and HDL-c (high-density lipoprotein cholesterol) [WMD: 4.16 (95%CI: 3.30, 5.01; P < 0.001, I2 = 82%)] following cumin intake. No changes were found in controls.
Conclusions
Cumin improves anthropometric and metabolic indices in overweight and/or type 2 diabetic subjects. The changes were related to the clinical condition and quality assessment.
Original language | English |
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Pages (from-to) | 313-321 |
Journal | Journal of Functional Foods |
Volume | 44 |
Early online date | 23 Mar 2018 |
DOIs | |
Publication status | E-pub ahead of print - 23 Mar 2018 |
Keywords
- Cumin
- Anthropometrics
- Glycaemic status
- Lipid profile
- Type 2 diabetes
- Overweight