TY - JOUR
T1 - A meta-analysis of cumin (Cuminum cyminim L.) consumption on metabolic and anthropometric indices in overweight and type 2 diabetics
AU - Jafarnejad, Sadegh
AU - Tsang, Catherine
AU - Taghizadeh, Moshen
AU - Zatollah, Asemi
AU - Keshavarz, Seyed Ali
PY - 2018/3/23
Y1 - 2018/3/23
N2 - Objective
To conduct a systematic review, including meta-analysis, of published randomised controlled trials (RCTs) of cumin to determine the effect on anthropometric and metabolic indices in overweight and/or type 2 diabetics, relative to controls.
Methods
Studies were identified by a search of electronic databases before December 2017. Combined and stratified analyses were used.
Results
Seven trials were identified, and data from 412 subjects were included. Pooled analysis showed improvements in bodyweight, body mass index (BMI) and fasting blood glucose (FBG) by −1.74 kg, −0.67 kg/m2 and −17.82 mg/dL respectively. Significant findings were also observed in triglycerides (TG) [WMD: −21.23 (95% CI: −37.64 to −4.82; P < 0.001, I2 = 92%)] and HDL-c (high-density lipoprotein cholesterol) [WMD: 4.16 (95%CI: 3.30, 5.01; P < 0.001, I2 = 82%)] following cumin intake. No changes were found in controls.
Conclusions
Cumin improves anthropometric and metabolic indices in overweight and/or type 2 diabetic subjects. The changes were related to the clinical condition and quality assessment.
AB - Objective
To conduct a systematic review, including meta-analysis, of published randomised controlled trials (RCTs) of cumin to determine the effect on anthropometric and metabolic indices in overweight and/or type 2 diabetics, relative to controls.
Methods
Studies were identified by a search of electronic databases before December 2017. Combined and stratified analyses were used.
Results
Seven trials were identified, and data from 412 subjects were included. Pooled analysis showed improvements in bodyweight, body mass index (BMI) and fasting blood glucose (FBG) by −1.74 kg, −0.67 kg/m2 and −17.82 mg/dL respectively. Significant findings were also observed in triglycerides (TG) [WMD: −21.23 (95% CI: −37.64 to −4.82; P < 0.001, I2 = 92%)] and HDL-c (high-density lipoprotein cholesterol) [WMD: 4.16 (95%CI: 3.30, 5.01; P < 0.001, I2 = 82%)] following cumin intake. No changes were found in controls.
Conclusions
Cumin improves anthropometric and metabolic indices in overweight and/or type 2 diabetic subjects. The changes were related to the clinical condition and quality assessment.
KW - Cumin
KW - Anthropometrics
KW - Glycaemic status
KW - Lipid profile
KW - Type 2 diabetes
KW - Overweight
U2 - 10.1016/j.jff.2018.03.026
DO - 10.1016/j.jff.2018.03.026
M3 - Article (journal)
SN - 1756-4646
VL - 44
SP - 313
EP - 321
JO - Journal of Functional Foods
JF - Journal of Functional Foods
ER -
