TY - JOUR
T1 - 3D printing in Ophthalmology: From medical implants to personalised medicine
AU - Tan, Greymi
AU - Ioannou, Nicole
AU - Mathew, Essyrose
AU - Tagalakis, Aristides D
AU - Lamprou, Dimitrios A
AU - Yu-Wai-Man, Cynthia
PY - 2022/8/9
Y1 - 2022/8/9
N2 - 3D printing was invented thirty years ago. However, its application in healthcare became prominent only in recent years to provide solutions for drug delivery and clinical challenges, and is constantly evolving. This cost-efficient technique utilises biocompatible materials and is used to develop model implants to provide a greater understanding of human anatomy and diseases, and can be used for organ transplants, surgical planning and for the manufacturing of advanced drug delivery systems. In addition, 3D printed medical devices and implants can be customised for each patient to provide a more tailored treatment approach. The advantages and applications of 3D printing can be used to treat patients with different eye conditions, with advances in 3D bioprinting offering novel therapy applications in ophthalmology. The purpose of this review paper is to provide an in-depth understanding of the applications and advantages of 3D printing in treating different ocular conditions in the cornea, glaucoma, retina, lids and orbits. [Abstract copyright: Copyright © 2022 The Author(s). Published by Elsevier B.V. All rights reserved.]
AB - 3D printing was invented thirty years ago. However, its application in healthcare became prominent only in recent years to provide solutions for drug delivery and clinical challenges, and is constantly evolving. This cost-efficient technique utilises biocompatible materials and is used to develop model implants to provide a greater understanding of human anatomy and diseases, and can be used for organ transplants, surgical planning and for the manufacturing of advanced drug delivery systems. In addition, 3D printed medical devices and implants can be customised for each patient to provide a more tailored treatment approach. The advantages and applications of 3D printing can be used to treat patients with different eye conditions, with advances in 3D bioprinting offering novel therapy applications in ophthalmology. The purpose of this review paper is to provide an in-depth understanding of the applications and advantages of 3D printing in treating different ocular conditions in the cornea, glaucoma, retina, lids and orbits. [Abstract copyright: Copyright © 2022 The Author(s). Published by Elsevier B.V. All rights reserved.]
KW - Drug delivery
KW - Ophthalmology
KW - Personalised medicine
KW - Implants
KW - 3D printing
U2 - 10.1016/j.ijpharm.2022.122094
DO - 10.1016/j.ijpharm.2022.122094
M3 - Article (journal)
C2 - 35952803
SN - 0378-5173
VL - 625
SP - 122094
JO - International Journal of Pharmaceutics
JF - International Journal of Pharmaceutics
ER -