Research output per year
Research output per year
Project Details
Description
Optimisation of a flow-based human in vitro blood-brain barrier system to replace animal models for studying immunopathology of viral brain infections
| Status | Finished |
|---|---|
| Effective start/end date | 1/09/12 → 31/03/16 |
UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This project contributes towards the following SDG(s):
Keywords
- Blood-brain barrier
- Encephalitis
- Brain infections
- Flavivirus
- Japanese encephalitis virus
Fingerprint
Explore the research topics touched on by this project. These labels are generated based on the underlying awards/grants. Together they form a unique fingerprint.
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DIPG-03. TARGETING PI3K USING THE BLOOD BRAIN BARRIER PENETRABLE INHIBITOR, GDC-0084, FOR THE TREATMENT OF DIFFUSE INTRINSIC PONTINE GLIOMA (DIPG)
Duchatel, R., Jackson, E., Patabendige, A., Cain, J., Tsoli, M., Monje, M., Alvaro, F., Ziegler, D. & Dun, M., 1 Apr 2019, In: Neuro-Oncology.Research output: Contribution to journal › Article (journal) › peer-review
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Brain microvascular endothelial-astrocyte cell responses following Japanese encephalitis virus infection in an in vitro human blood-brain barrier model
Patabendige, A., Michael, B. D., Craig, A. G. & Solomon, T., 30 Jun 2018, In: Molecular and Cellular Neurosciences. 89, p. 60-70 11 p.Research output: Contribution to journal › Article (journal) › peer-review
61 Citations (Scopus) -
Japanese encephalitis virus infection increases blood-brain barrier permeability in a human model by inducing a strong pro-inflammatory endothelial response
Patabendige, A., Michael, B. D., Craig, A. G. & Solomon, T., 9 Apr 2018Research output: Other contribution