Research output per year
Research output per year
Personal profile
Biography
Philip has been the Associate Head of Postgraduate Medical Education at Edge Hill University since 2021. He is also the Medical School lead for Academic Quality and Enhancement. He is a Pharmacologist and member of the British Pharmacological Society (BPS) actively contributing to pharmacology teaching across both postgraduate and undergraduate programmes within the Faculty of Health, Social Care and Medicine.
Philip’s current research interest is in the development of novel therapies for the treatment of brain tumours. Current projects include the development of novel Cyclin Dependent Kinase (CDK) inhibitors for the treatment of glioblastoma and the identification and characterisation of non-Poly(ADP-Ribose) Polymerase 1 targets of olaparib for the treatment of glioblastoma and neuroblastoma. Ongoing projects include the supervision of PhD students based at Edge Hill and with collaborators at the University of Central Lancashire.
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Education/Academic qualification
Dioplóma sa Ghaeilge, PGDip, National University of Ireland, Galway
Oct 2008 → Jul 2010
Award Date: 1 Jul 2010
Biochemistry and Molecular Pharmacology, PhD, Pharmacological characterisation of the human 5-HT1A receptor and its inhibitory G-protein fusions, University of Glasgow
Sept 1998 → Oct 2001
Award Date: 1 Oct 2001
BSc (Hons) Pharmacology, BSc, University of Aberdeen
Sept 1992 → Jul 1996
Award Date: 1 Jul 1996
Other positions
External Examiner - University of Portsmouth, University of Portsmouth
1 Sept 2021 → 30 Sept 2025
External Examiner - The University of Manchester, University of Manchester
1 May 2021 → 31 Dec 2024
Research Institutes
- Health Research Institute
Research Centres
- Cardio-Respiratory Research Centre
- Data Science STEM Research Centre
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Collaborations and top research areas from the last five years
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Research output
- 5 Article (journal)
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Multidisciplinary docking, kinetics and X-ray crystallography studies of baicalein acting as a glycogen phosphorylase inhibitor and determination of its’ potential against glioblastoma in cellular models
Mathomes, R. T., Koulas, S. M., Tsialtas, I., Stravodimos, G., Welsby, P. J., Psarra, A-M. G., Stasik, I., Leonidas, D. D. & Hayes, J. M., 3 Jun 2023, (E-pub ahead of print) In: Chemico-Biological Interactions. 382, p. 110568 110568.Research output: Contribution to journal › Article (journal) › peer-review
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The effect of cryoprotectants and storage conditions on the transfection efficiency, stability and safety of lipid-based nanoparticles for mRNA and DNA delivery
Kafetzis, K., Papalamprou, N., Mcnulty, E., Thong, K., Sato, Y., Mironov, A., Purohit, A., WELSBY, PHILIP., Harashima, H., Yu-Wai-Man, C. & TAGALAKIS, ARISTIDES., 2023, In: Advanced healthcare materials.Research output: Contribution to journal › Article (journal) › peer-review
Open Access -
Structure-Based Design of Potent Selective Nanomolar Type-II Inhibitors of Glycogen Synthase Kinase-3β
Davies, M. P., Benitz, R., Perez, C., Jakupovic, S., WELSBY, PHILIP., Rzepecka, K., Alder, J., Davidson, C., Martinez, A. & Hayes, J. M., 11 Feb 2021, In: Journal of Medicinal Chemistry. 64, 3, p. 1497–1509 12 p.Research output: Contribution to journal › Article (journal) › peer-review
Open AccessFile7 Citations (Scopus)1 Downloads (Pure) -
Clathrin-mediated endocytic uptake of PUFA enriched self-nanoemulsifying lipidic systems (SNELS) of an anticancer drug against triple negative cancer and DMBA induced preclinical tumor model
Khurana, R. K., Kumar, R., Gaspar, B. L., Welsby, G., Welsby, P., Kesharwani, P., Katare, O. P., Singh, K. K. & Singh, B., 1 Oct 2018, In: Materials Science and Engineering C. 91, p. 645-658 14 p.Research output: Contribution to journal › Article (journal) › peer-review
16 Citations (Scopus) -
Pharmacological effects of asiatic acid in glioblastoma cells under hypoxia
Thakor, F. K., Wan, K-W., Welsby, P. J. & Welsby, G., 30 Jun 2017, In: Molecular and Cellular Biochemistry. 430, 1-2, p. 179-190 12 p.Research output: Contribution to journal › Article (journal) › peer-review
Open AccessFile16 Citations (Scopus)62 Downloads (Pure)