Personal profile
Biography
Katja is a Senior Lecturer in Biomedical Science, and the Teaching and Learning lead at the Biology department. Katja leads the BSc (Hons) Biomedical Science programme and line manager for the GTAs at the Biology department.
Katja is the deputy chair of the Health-related Research Ethics Committee (HREC). Katja is a member of VASP. Katja is a University Learning Teaching Fellow (FAS).
Katja is a Fellow of the Institute of Biomedical Science (IBMS) and a Senior Fellow of AdvanceHE (SFHEA).
Katja has previously worked at the Medical School Innsbruck (Austria) and the University of Cologne (Germany) and has been guest scientist at the University of Vienna, University of Tel Aviv and at Barts and The London School of Medicine and Dentistry while expanding her expertise into rare genetic skin diseases and prospective causative treatment options.
Research interests
Katja’s research group studies rare skin conditions, namely autosomal recessive congenital ichthyosis (ARCI) with a focus on developing causative treatment strategies. One focus on research is the development of protein replacement therapy for Tgase1-deficient ARCI patients by means of molecular farming. A second line of research interest is the gene NIPAL4, encoding NIPA4.
Katja has previously developed 3D skin models for health and ARCI skin which have been patented in in 2009 and are widely used by the dermatological and pharmaceutical and cosmetic industries. 3D skin models support the global aim reducing animals in drug development. With an ever-increasing demand to provide vegan skin care products, this research team is now advancing existing 3D skin models and generate animal-components-free modelling systems.
Teaching-led research is informed by student and societal demands: Post-pandemic learning experiences for undergraduate students and career development needs for GTAs.
External engagement
Katja is the Training School Coordinator for the COST Action CA21108 (Netskinmodels, 20222-2026). This pan-European research and training network, funded by the EU, aims to improve skin modelling applications for research and industry. Skin can be modelled and mimicked throuhg computer tool (in-silico), with bioprinting and organ-on-chip applications and through in-vitro skin modelling technology. Skin models can aid the understanding of diseases, advance drug development and signficant reduce the use of animals in medical and biomedical research.
Training School invite early career scientstist to in-person and remote training events (all attendance fully paid by COST), covering on-demand topics in skin biology, cell culture and 3D modelling. The Training School Coordinator orchestrates all training events across all 42 COST Action nations.
Education/Academic qualification
Biochemistry, MSc, Free University of Berlin
Genetics, PhD, University of Cologne
Keywords
- RL Dermatology
- rare skin diseases
- epidermis
- ichthyosis
- epidermal barrier
- keratinocytes
- melanocytes
- keratins
- genes
- NGS
- 3D skin modelling
- support groups
- patient-directed
- Tgase-1
- Human genetics
- new gene discovery
- genetic counselling
- functional analysis
- NIPAL4
- ALOX12B
- RM Therapeutics. Pharmacology
- protein replacement therapy
- patient-specific therapy
- nanoparticles
- nanogel
- temperature-sensitive delivery system
- side-effects
- molecular pharming
- bioreactor
- suspension culture
- recombiant proteins
- animal-free
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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SDG 3 Good Health and Well-being
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SDG 4 Quality Education
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SDG 5 Gender Equality
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SDG 9 Industry, Innovation, and Infrastructure
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SDG 10 Reduced Inequalities
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Collaborations and top research areas from the last five years
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Critical evaluation of animal-component-free media in human keratinocytes and human fibroblasts
BYRON, E. & ECKL, K., 28 Apr 2025.Research output: Contribution to conference › Poster
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Learn!Bio—A time-limited cross-sectional study on biosciences students’ pathway to resilience during and post the Covid-19 pandemic at a UK university from 2020–2023 and insights into future teaching approaches
ECKL, K., ANDREWS, K. & STONELEY, R., 30 Sept 2025, In: PLoS ONE. 20, 9, p. 1-13 e0300824.Research output: Contribution to journal › Article (journal) › peer-review
Open AccessFile4 Downloads (Pure) -
Generation of a sodium alginate scaffold to be used as an extracellular matrix for an animal-free 3d skin model
BYRON, E. & ECKL, K., 7 Dec 2023.Research output: Contribution to conference › Speech
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Quality of life and clinical characteristics of self-improving congenital ichthyosis within the disease spectrum of autosomal recessive congenital ichthyosis
Hake, L., Süßmuth, K., Komlosi, K., Kopp, J., Drerup, C., Metze, D., Traupe, H., Hausser, I., ECKL, K., Hennies, H., Fischer, J. & Oji, V., 1 Apr 2022, In: Journal of the European Academy of Dermatology and Venereology. 36, 4, p. 582-591 10 p.Research output: Contribution to journal › Article (journal) › peer-review
Open AccessFile11 Link opens in a new tab Citations (Scopus)140 Downloads (Pure) -
Cystatin M/E Variant Causes Autosomal Dominant Keratosis Follicularis Spinulosa Decalvans by Dysregulating Cathepsins L and V
ECKL, K., 12 Jul 2021, In: Frontiers in Genetics. 12, 689940.Research output: Contribution to journal › Article (journal) › peer-review
Open AccessFile10 Link opens in a new tab Citations (Scopus)119 Downloads (Pure)
Projects
- 1 Active
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NETSKINMODELS: CA21108 - European Network for Skin Engineering and Modeling (NETSKINMODELS)
Dubrac, S. (PI) & ECKL, K. (PI)
15/09/22 → 14/10/26
Project: Research
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COST Action CA21108 Training School at the University of Porto at Prof Joana Loureiro's lab (Mechanical Engineering Department at the LEPABE - Laboratory for Process Engineering, Environment, Biotechnology and Energy).
ECKL, K. (Participant)
2 Feb 2026 → 6 Feb 2026Activity: Events › Organising a conference, workshop, etc.
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Planning and organising an international in-person Training School for the COST Action CA211108 (NETSKINMODELS) in the Netherlands
ECKL, K. (Organiser)
Jul 2025 → Aug 2025Activity: Events › Organising a conference, workshop, etc.
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Hosting an academic visitor -Zeynep Püren Yildirim
ECKL, K. (Other) & BYRON, E. (Other)
1 Mar 2025 → 30 Apr 2025Activity: Other activity types › Other
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Planning, organising and delivery of a COST Action Training School on cell extraction and culture (basics in epidermal cell biology) in Istanbul, Turkey.
ECKL, K. (Organiser), BYRON, E. (Participant), STONELEY, R. (Participant) & Türker Baran, E. (Organiser)
21 Jul 2024 → 26 Jul 2024Activity: Events › Organising a conference, workshop, etc.