Research output per year
Research output per year
Personal profile
Biography
Biography
Jayne is a Senior Lecturer in Biomedical Science, having joined Edge Hill University in 2015 with a special focus on reproductive biology- namely implantation, placental development and the Developmental Origins of Health and Disease (DOHaD).
Following a BSc. (Hons) in Anatomical Sciences, Jayne obtained her PhD at the University of Manchester where she studied the role of cytotrophoblast in driving placental vascular development with Prof John Aplin and Prof Melissa Westwood. She subsequently worked in the field of wound healing, with a focus on impaired restoration of diabetic wounds, before returning to Maternal and Fetal Health research to investigate potential treatments for Fetal Growth Restriction.
Research
Jayne's current research centres on understanding of placental blood vessel formation, placental stem cells, regulators of implantation, pregnancy in polycystic ovary syndrome, prenatal programming and nutrition, with expertise in vitro models of cell function.
Alongside research, Jayne has a keen interest in Public Engagement in science, having volunteered for many years as a STEM Ambassador and collaborating on the design and delivery of outreach sessions for local schools, colleges and youth groups- in particular the Scout Association.
Teaching
Jayne is Module Leader for Level 4 Core Module Biology in Practice as well as Level 6 Pathology, and currently contributes to the delivery of Level 4 Biology in Practice and Anatomy and Physiology, Level 6 Advanced Tissue Applications, enjoys hosting Final Year Project students in her lab and has experience in teaching Pharmacology, Current Issues in Biology, Biology of Disease, Genetics for Midwives and MBChB Embryology, Teratogens and Malformations.
PhD and MRes External Examining
- University of Manchester (2026)
- University of Lancashire (2024)
- University of Leeds (2024)
Manuscript Reviewing
Cell Communication and Signalling; Reproductive Biology and Endocrinology, Biological Research
Grant Reviewing
MRC, Austrian Science Funds, British Heart Foundation Fellowships
Education/Academic qualification
Maternal and Fetal Health, PhD, The Role of the Cytotrophoblast in Driving Placental Vascular Development, University of Manchester
Award Date: 1 Mar 2010
Anatomical Sciences, BSc, BSc.(Hons) Anatomical Sciences with Year in Industry, University of Manchester
Award Date: 1 Jul 2006
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Collaborations and top research areas from the last five years
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The myomiRs, miR-1-3p and miR-133a-3p regulate the differentiation potential of placental mesenchymal stromal cells towards a vascular smooth muscle cell lineage
Kennedy, M. G., Byford, A. R., Sayers, K., Shao, Z., Harper, C. V., Charnock, J. C., Holder, B., Pensabene, V., Scott, E. M. & Forbes, K., 14 Nov 2025, (E-pub ahead of print) In: Placenta. 171, p. e233 1 p.Research output: Contribution to journal › Meeting Abstract › peer-review
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Trophoblast-derived factors drive human mesenchymal stem cell differentiation along an endothelial lineage: A model of early placental vasculogenesis
Harper, C. V., Eccles, L., Henstock, J. & Charnock, J. C., 31 Mar 2025, In: Reproductive Biology. 25, 1, p. 1-8 8 p., 100994.Research output: Contribution to journal › Article (journal) › peer-review
Open AccessFile1 Link opens in a new tab Citation (Scopus)32 Downloads (Pure) -
Using mixed methods to explore dietary intake in women with recurrent miscarriage: integrating Participant Public Involvement in the research design
KOROMA, F., CHARNOCK, J., Bambang, K. & Abayomi, J. C., 16 Dec 2024, In: Proceedings of the Nutrition Society. 83 , OCE4, p. 1-1 E290.Research output: Contribution to journal › Conference proceeding article (ISSN) › peer-review
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Cytotrophoblast-derived factors drive mesenchymal stem cell differentiation along an endothelial lineage: A model of early placental vasculogenesis
HARPER, C., Eccles, L., Henstock, J. & CHARNOCK, J., 26 Aug 2021.Research output: Contribution to conference › Abstract › peer-review
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Increased levels of testosterone associated with polycystic ovary syndrome (PCOS) negatively affects HOXA10 and integrin beta-3 expression in endometrial cells and embryo attachment using a trophoblast cell spheroid model
HARPER, C., SIDAT, R., Reeves, B., MARRIOTT, A. & CHARNOCK, J., 18 Oct 2021.Research output: Contribution to conference › Abstract › peer-review