Personal profile
Biography
Dr Aristides Tagalakis is a Reader in Gene Delivery and Nanomedicine at Edge Hill University. The main objective of his research has been the development and implementation of innovative non-viral and nanoparticle technologies in gene therapy for solid tumours, cystic fibrosis, glaucoma, neurological and cardiovascular disorders. These have included a variety of somatic gene transfer approaches towards the efficient, widespread and long-term expression of recombinant genes locally or systemically, silencing of disease-implicated genes, as well as gene repair/editing.
Previously he worked as a Research Fellow and then a Senior Research Fellow at UCL, where he is now an Associate Professor. He holds a PhD from The University of London. He has authored over 90 peer-reviewed publications (original research articles and conference proceedings) in high-impact international journals. He is a member of the ‘Nanoagents and Synthetic Formulations Scientific Committee’ of the American Society of Gene and Cell Therapy. He is a reviewer of national and international project/programme grants and a regular reviewer of over 50 leading scientific journals. He serves on editorial boards of scientific journals. He is a Fellow of: the Institute of Biomedical Sciences, the Royal Society of Biology, the British Society for Nanomedicine and the Higher Education Academy. He is also a Full Member of the Biochemical Society, the Oligonucleotide Therapeutics Society and the American Society of Gene and Cell Therapy.
Other positions
Associate Professor, University College London
Research Centres
- Centre for Intelligent Visual Computing Research
- Data Science STEM Research Centre
Fingerprint
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Collaborations and top research areas from the last five years
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Low Molecular Weight Alginate Oligosaccharides as Alternatives to PEG for Enhancement of the Diffusion of Cationic Nanoparticles Through Cystic Fibrosis Mucus
Maeshima, R., Tagalakis, A. D., Gyftaki-Venieri, D., Jones, S. A., Rye, P. D., Tøndervik, A., Åstrand, O. A. H. & Hart, S. L., 13 Nov 2024, (E-pub ahead of print) In: Advanced healthcare materials. 14, 1, p. 1-14 2400510.Research output: Contribution to journal › Article (journal) › peer-review
Open AccessFile3 Link opens in a new tab Citations (Scopus)40 Downloads (Pure) -
Manufacturing and characterisation of 3D-printed sustained-release Timolol implants for glaucoma treatment
Paleel, F., Qin, M., TAGALAKIS, A., Yu-Wai-Man, C. & Lamprou, D., 5 Apr 2024, In: Drug Delivery and Translational Research. p. 242-252 11 p.Research output: Contribution to journal › Article (journal) › peer-review
Open AccessFile10 Link opens in a new tab Citations (Scopus)40 Downloads (Pure) -
3D-printed long-acting 5-fluorouracil implant to prevent conjunctival fibrosis in glaucoma
Ioannou, N., Luo, J., Qin, M., Di Luca, M., Mathew, E., Tagalakis, A. D., Lamprou, D. A. & Yu-Wai-Man, C., 6 Jan 2023, (E-pub ahead of print) In: Journal of Pharmacy and Pharmacology. 75, 2, p. 276-286 11 p.Research output: Contribution to journal › Article (journal) › peer-review
Open AccessFile16 Link opens in a new tab Citations (Scopus)134 Downloads (Pure) -
Adrenaline blocks key cell cycle genes and exhibits antifibrotic and vasoconstrictor effects in glaucoma surgery
TAGALAKIS, A., Thong, K., Andriesei, P., Luo, J., Qin, M., Ng, J., Hysi, P. & Yu-Wai-Man, C., 8 Jul 2023, (E-pub ahead of print) In: Experimental Eye Research. 233, 109561.Research output: Contribution to journal › Article (journal) › peer-review
Open AccessFile7 Link opens in a new tab Citations (Scopus)177 Downloads (Pure) -
Blood–brain barrier disruption in dementia: Nano‐solutions as new treatment options: Nano-solutions as new treatment options
Cooper, C. G., Kafetzis, K. N., Patabendige, A. & Tagalakis, A. D., 28 Dec 2023, In: The European journal of neuroscience. 59, 6, p. 1359-1385 27 p.Research output: Contribution to journal › Article (journal) › peer-review
Open AccessFile6 Link opens in a new tab Citations (Scopus)154 Downloads (Pure)
Impacts
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Translating Automated Facial Appearance Assessment Model into Clinical Practice Tool for Cleft Lip Outcome Evaluation
BAKAKI, P. (Participant), LIU, Y. (Participant), PEREIRA, E. (Participant), TAGALAKIS, A. (Participant), Richard, B. (Participant) & Chadha, A. (Participant)
Impact: Health impacts
Activities
- 2 Research degree supervision
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Epigenetic changes in lung cancer diagnosis and therapy
TAGALAKIS, A. (Director of Studies), Liloglou, L. (Supervisor) & REHMAN, I. (Participant)
2023 → …Activity: Other activity types › Research degree supervision
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The Development and Functionalisation of a Novel Blood-Brain Barrier Penetrating Nanogel for Targeted Treatment of Alzheimer’s Disease'
TAGALAKIS, A. (Director of Studies), Liloglou, L. (Supervisor) & COOPER, C. (Participant)
2022 → …Activity: Other activity types › Research degree supervision