Personal profile
Research interests
I am an enthusiastic and inquisitive life scientist fascinated by the evolutionary and molecular biology of host-microbe interactions.
How does the crosstalk between bacteria and their animal hosts work and how has it evolved over time?
What role does the immune system play in host-microbe interactions?
What is the decision-making process that leads to a particular immune response?
These are some of the questions that have captivated me in my past and current work. Previously, my colleagues and I have characterised the transcriptional response of cnidarian and C. elegans invertebrate models to bacterial exposure and uncovered genes that are central to the innate immune response of these organisms, with evolutionary and potential functional conservation in humans. These discoveries have allowed us to understand how specific and fine-tuned innate immune responses can be. In the future, I would like to explore how the natural evolution of the immune system can help us treat infectious disease today.
My aim is to understand how interactions between animals and microbes work and evolve, how they influence each other’s health and the conditions that lead to disease. I believe that this knowledge can be harnessed to improve human health.
I am passionate about teaching, promoting research integrity, and want to motivate students and the public to be curious about innate immunity, host-microbe interactions and seeking answers to relevant questions.
Biography
CAREER STEPS
02.2024-present
Lecturer in Biomedical Science. Edge Hill University, UK.
Main activities:
- Research and teaching academic permanent position.
02.2020-01.2024 Senior Research Associate. Lancaster University, UK.
Main activities:
- Research on a BBSRC-funded grant to study integrated multiomics (dual-transcriptomics, proteomics, and targeted metabolomics) of host-bacteria interactions during C. elegans gut infections.
- Research laboratory management and UG/MSc student supervision.
- Voluntary teaching of skills and statistics workshops for graduate students.
- Service representing staff researchers in Faculty Committees for Research and Equality, Diversity, and Inclusion.
- Facilitation of the writing group organised by the Women’s Staff Network.
Supervisor: Dr. Alexandre Benedetto
05.2018–01.2020 Postdoctoral Research Associate. Christian-Albrechts University Kiel, Germany.
Main activities:
- Research on a DFG-funded grant towards the identification of molecular mechanisms of high immune specificity in C. elegans. Data analysis, presentation at scientific conferences, divulgation of research findings to boarder public, preparation of scientific manuscripts and research bid applications.
- Organisation of the departmental seminar, UG/MSc teaching in Genetics, Ecology and Immunology courses, and student research project supervision.
Supervisors: Dr. Katja Dierking and Prof. Dr. Hinrich Schulenburg
01.2014–05.2018 Doctoral candidate-PhD in Natural Sciences (magna cum laude). Max Planck Institute for Evolutionary Biology Plön, Germany/Christian-Albrechts University Kiel, Germany
Main activities
- Research towards writing the dissertation titled: “High specificity in C. elegans innate immune responses”.
- Supervision of practical students, bachelor theses and assistance with basic and advanced ecology, evolution, and immunity courses.
Supervisors: Dr. Katja Dierking and Prof. Dr. Hinrich Schulenburg
01.2011–12.2013 MSc in Biology (Emphasis in Genetics). Universidad Nacional de Colombia.
Main activities
- Research towards writing the dissertation titled: “Transcriptomic response of the hydrozoan Hydractinia symbiolongicarpus after a bacterial challenge”.
- Lab management and purchase orders.
- Supervision of practical students.
Supervisor: Prof. Dr. Luis F. Cadavid
01.2011–12.2012 University teaching assistant (assistant professor scholarship). Universidad Nacional de Colombia.
Main activities:
-Teaching undergraduate level genetics and ecology courses.
01.2007–12.2010 Undergraduate teaching assistant (Undergraduate scholarship). Universidad Nacional de Colombia.
Main activities:
-Support with teaching undergraduate level genetics and ecology courses and with ecology field work.
08.2006–12.2010 BSc in Biology (first of class). Universidad Nacional de Colombia.
Education/Academic qualification
Natural Sciences, PhD, “High specificity in C. elegans innate immune responses”., Max Planck Society
1 Jan 2014 → 15 May 2018
Award Date: 15 May 2018
Other positions
Visiting Researcher, Lancaster University
1 Feb 2024 → 31 Jul 2025
Keywords
- Q Science
- Biology
- Genetics
- Evolution
- Gene regulation
- Metabolism
- QL Zoology
- Caenorhabditis elegans
- Invertebrate Models
- QR Microbiology
- Infection
- Microbiota
- QR180 Immunology
- Innate Immunity
- Host-microbe Interactions
- Host-pathogen Interactions
- Evolutionary Immunology
Research Centres
- Centre for Human Animal Studies
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
-
SDG 3 Good Health and Well-being
-
SDG 9 Industry, Innovation, and Infrastructure
Fingerprint
- 1 Similar Profiles
Collaborations and top research areas from the last five years
-
Unanticipated specificity in effector-triggered immunity
Zárate-Potes, A., Schulenburg, H. & Dierking, K., 15 Nov 2024, (E-pub ahead of print) In: Trends in Immunology. 45, 12, p. 939-942 4 p.Research output: Contribution to journal › Short survey › peer-review
Open Access3 Link opens in a new tab Citations (Scopus) -
High-Throughput Screening of Microbial Isolates with Impact on <em>Caenorhabditis elegans</em> Health
Ali, I., Martin, J., Zárate-Potes, A. & Benedetto, A., 28 Apr 2022, In: Journal of Visualized Experiments. 2022, 182, e63860.Research output: Contribution to journal › Article (journal) › peer-review
Open AccessFile2 Link opens in a new tab Citations (Scopus)68 Downloads (Pure) -
Meta-Analysis of Caenorhabditis elegans Transcriptomics Implicates Hedgehog-Like Signaling in Host-Microbe Interactions
Zárate-Potes, A., Ali, I., Ribeiro Camacho, M., Brownless, H. & Benedetto, A., 10 May 2022, In: Frontiers in Microbiology. 13, p. 1-17 17 p.Research output: Contribution to journal › Article (journal) › peer-review
Open AccessFile8 Link opens in a new tab Citations (Scopus)34 Downloads (Pure) -
Effector and regulator: Diverse functions of C. elegans C-type lectin-like domain proteins
Pees, B., Yang, W., Kloock, A., Petersen, C., Peters, L., Fan, L., Friedrichsen, M., Butze, S., Zárate-Potes, A., Schulenburg, H. & Dierking, K., 1 Apr 2021, In: PLoS Pathogens. 17, 4, p. 1-25 25 p., e1009454.Research output: Contribution to journal › Article (journal) › peer-review
Open Access35 Link opens in a new tab Citations (Scopus) -
Guard proteins keep watch at epithelial walls
Zarate-Potes, A. & Dierking, K., 13 Jul 2021, In: Immunity. 54, 7, p. 1366-1368 3 p.Research output: Contribution to journal › Article (journal) › peer-review
-
Lancaster University
ZARATE-POTES, A. (Visiting researcher)
1 Feb 2024 → 31 Jul 2025Activity: Visiting & honorary positions › External honorary positions
-
Podcast Episode 100 Years 100 Objects 55. Nursing Notebook
ZARATE-POTES, A. (Participant)
11 Jul 2023Activity: Other activity types › Other
-
Journal of Visualized Experiments (Journal)
ZARATE-POTES, A. (Reviewer)
1 Jan 2022Activity: Peer-review & editorial work › Publication Peer-review
-
Genetics (Journal)
ZARATE-POTES, A. (Reviewer)
1 Jan 2022Activity: Peer-review & editorial work › Publication Peer-review
-
Frontiers in Microbiology (Journal)
ZARATE-POTES, A. (Reviewer)
1 Jan 2022Activity: Peer-review & editorial work › Publication Peer-review