Research output per year
Research output per year
- 33 results
Search results
-
2023
Blood–brain barrier disruption in dementia: Nano‐solutions as new treatment options: Nano-solutions as new treatment options
Cooper, C. G., Kafetzis, K. N., Patabendige, A. & Tagalakis, A. D., 28 Dec 2023, In: The European journal of neuroscience. p. 1-27 27 p.Research output: Contribution to journal › Article (journal) › peer-review
Open AccessFile34 Downloads (Pure) -
EXTH-36. COMBINING ONC201 AND PAXALISIB FOR THE TREATMENT OF DIFFUSE MIDLINE GLIOMA (DMG); THE PRECLINICAL RESULTS UNDERPINNING THE INTERNATIONAL PHASE II CLINICAL TRIAL (NCT05009992)
Jackson, E., Duchatel, R., Staudt, D., Persson, M., Mannan, A., Yadavilli, S., Parackal, S., Game, S., Chong, W. C., Jayasekara, W. S., Grand, M. L., Kearney, P., Douglas, A., Findlay, I., Germon, Z., McEwen, H., Beitaki, T., Patabendige, A., Skerrett-byrne, D. & Nixon, B. & 28 others, , 10 Nov 2023, In: Neuro-Oncology. 25, Supplement_5, p. v232-v232Research output: Contribution to journal › Article (journal) › peer-review
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ONC201 in combination with paxalisib for the treatment of H3K27-altered diffuse midline glioma
Jackson, E. R., Duchatel, R. J., Staudt, D. E., Persson, M. L., Mannan, A., Yadavilli, S., Parackal, S., Game, S., Chong, W. C., Jayasekara, W. S. N., Le Grand, M., Kearney, P. S., Douglas, A. M., Findlay, I. J., Germon, Z. P., McEwen, H. P., Beitaki, T. S., Patabendige, A., Skerrett-Byrne, D. A. & Nixon, B. & 28 others, , 17 May 2023, In: Cancer Research. p. 1-17Research output: Contribution to journal › Article (journal) › peer-review
Open AccessFile24 Citations (Scopus)25 Downloads (Pure) -
The role of the blood-brain barrier during neurological disease and infection
Patabendige, A. & Janigro, D., 17 Mar 2023, (E-pub ahead of print) In: Biochemical Society Transactions. 51, 2, p. 1-14Research output: Contribution to journal › Article (journal) › peer-review
Open AccessFile21 Citations (Scopus)47 Downloads (Pure) -
2022
An Improved In Vitro Porcine Blood-Brain Barrier Model for Permeability Screening and Functional Studies
Patabendige, A., 23 Jun 2022, The blood-brain barrier. Stone, N. (ed.). Vol. 2492. p. 131-142 12 p. (Methods in molecular biology (Clifton, N.J.)).Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review
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Astrocytic aquaporin 4 subcellular translocation as a therapeutic target for cytotoxic edema in ischemic stroke
PATABENDIGE, A. & Chen, R., 29 Apr 2022, In: Neural Regeneration Research. 17, 12, p. 2666-2668Research output: Contribution to journal › Article (journal) › peer-review
Open AccessFile6 Citations (Scopus)130 Downloads (Pure) -
Editorial: Cerebrospinal fluid dynamics and intracranial pressure elevation-Novel insights on molecular and physiological mechanisms, and implications for neurological disease
Patabendige, A., Vinje, V. & Stoodley, M., 28 Dec 2022, In: Frontiers in Molecular Neuroscience. 15, p. 1-3 1119980.Research output: Contribution to journal › Editorial (journal)
Open AccessFile1 Citation (Scopus)35 Downloads (Pure) -
2021
Altered Cerebrospinal Fluid Clearance and Increased Intracranial Pressure in Rats 18 h After Experimental Cortical Ischaemia
Bothwell, S. W., Omileke, D., Hood, R. J., Pepperall, D. G., Azarpeykan, S., Patabendige, A. & Spratt, N. J., 9 Aug 2021, In: Frontiers in Molecular Neuroscience. 14, 712779.Research output: Contribution to journal › Article (journal) › peer-review
Open AccessFile7 Citations (Scopus)62 Downloads (Pure) -
Astrocyte Activation in Neurovascular Damage and Repair Following Ischaemic Stroke
Patabendige, A., Singh, A., Jenkins, S., Sen, J. & Chen, R., 20 Apr 2021, In: International Journal of Molecular Sciences. 22, 8, 4280.Research output: Contribution to journal › Article (journal) › peer-review
Open AccessFile116 Citations (Scopus)118 Downloads (Pure) -
Blood–brain barrier disruption in atrial fibrillation: a potential contributor to the increased risk of dementia and worsening of stroke outcomes?
Aryal, R. & Patabendige, A., 30 Apr 2021, In: Open Biology. 11, 4, p. 200396 200396.Research output: Contribution to journal › Article (journal) › peer-review
Open AccessFile14 Citations (Scopus)84 Downloads (Pure) -
CSF Secretion Is Not Altered by NKCC1 Nor TRPV4 Antagonism in Healthy Rats
Bothwell, S. W., Omileke, D., Patabendige, A. & Spratt, N. J., 30 Sept 2021, In: Brain Sciences. 11, 9, p. 1117 1117.Research output: Contribution to journal › Article (journal) › peer-review
Open AccessFile10 Citations (Scopus)42 Downloads (Pure) -
Decreased Intracranial Pressure Elevation and Cerebrospinal Fluid Outflow Resistance: A Potential Mechanism of Hypothermia Cerebroprotection Following Experimental Stroke
Omileke, D., Bothwell, S. W., Pepperall, D., Beard, D., Coupland, K., Patabendige, A. & Spratt, N. J., 30 Nov 2021, In: Brain Sciences. 11, 12, p. 1-10 1589.Research output: Contribution to journal › Article (journal) › peer-review
Open AccessFile6 Citations (Scopus)85 Downloads (Pure) -
Short-duration hypothermia completed prior to reperfusion prevents intracranial pressure elevation following ischaemic stroke in rats
Omileke, D., Azarpeykan, S., Bothwell, S. W., Pepperall, D., Beard, D. J., Coupland, K., Patabendige, A. & Spratt, N. J., 16 Nov 2021, In: Scientific Reports. 11, 1, 22354.Research output: Contribution to journal › Article (journal) › peer-review
Open AccessFile3 Citations (Scopus)58 Downloads (Pure) -
Short-Duration Hypothermia Induction in Rats using Models for Studies examining Clinical Relevance and Mechanisms
Omileke, D., Bothwell, S., Beard, D. J., Mackovski, N., Azarpeykan, S., Coupland, K., Patabendige, A. & Spratt, N., 3 Mar 2021, In: Journal of Visualized Experiments. 169, 10 p., 62325.Research output: Contribution to journal › Article (journal) › peer-review
Open Access4 Citations (Scopus) -
Ultra-Short Duration Hypothermia Prevents Intracranial Pressure Elevation Following Ischaemic Stroke in Rats
Omileke, D., Pepperall, D. G., Bothwell, S. W., Mackovski, N., Azarpeykan, S., Beard, D. J., Coupland, K., PATABENDIGE, A. & Spratt, N. J., 20 Sept 2021, In: Frontiers in Neurology. 12, 684353.Research output: Contribution to journal › Article (journal) › peer-review
Open AccessFile7 Citations (Scopus)49 Downloads (Pure) -
2020
Spinal cerebrospinal fluid flow is increased in rats with elevated intracranial pressure 18 hours after cortical ischaemic stroke
Bothwell, S., Omileke, D., Pepperall, D., Patabendige, A. & Spratt, N., 1 Oct 2020.Research output: Working paper › Preprint
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2019
Cerebrospinal fluid dynamics and intracranial pressure elevation in neurological diseases
Bothwell, S. W., Janigro, D. & Patabendige, A., 10 Apr 2019, In: Fluids and Barriers of the CNS. 16, p. 1-18 9.Research output: Contribution to journal › Article (journal) › peer-review
Open AccessFile172 Citations (Scopus)78 Downloads (Pure) -
Correction to: A26 Cerebrospinal fluid outflow resistance is increased following small-moderate ischaemic stroke.
Patabendige, A., MacKovski, N., Pepperall, D., Hood, R. & Spratt, N., 31 Jul 2019, In: Fluids and Barriers of the CNS.Research output: Contribution to journal › Article (journal) › peer-review
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DIPG-03. TARGETING PI3K USING THE BLOOD BRAIN BARRIER PENETRABLE INHIBITOR, GDC-0084, FOR THE TREATMENT OF DIFFUSE INTRINSIC PONTINE GLIOMA (DIPG)
Duchatel, R., Jackson, E., Patabendige, A., Cain, J., Tsoli, M., Monje, M., Alvaro, F., Ziegler, D. & Dun, M., 1 Apr 2019, In: Neuro-Oncology.Research output: Contribution to journal › Article (journal) › peer-review
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2018
Brain microvascular endothelial-astrocyte cell responses following Japanese encephalitis virus infection in an in vitro human blood-brain barrier model
Patabendige, A., Michael, B. D., Craig, A. G. & Solomon, T., 30 Jun 2018, In: Molecular and Cellular Neurosciences. 89, p. 60-70 11 p.Research output: Contribution to journal › Article (journal) › peer-review
56 Citations (Scopus) -
Japanese encephalitis virus infection increases blood-brain barrier permeability in a human model by inducing a strong pro-inflammatory endothelial response
Patabendige, A., Michael, B. D., Craig, A. G. & Solomon, T., 9 Apr 2018Research output: Other contribution
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2015
Ability of the Encephalitic Arbovirus Semliki Forest Virus To Cross the Blood-Brain Barrier Is Determined by the Charge of the E2 Glycoprotein.
Ferguson, M., Saul, S., Fragkoudis, R., Weisheit, S., Cox, J., Patabendige, A., Sherwood, K., Watson, M., Merits, A. & Fazakerley, J., 31 Aug 2015, In: Journal of Virology. 89, 15, p. 7536-7549 14 p.Research output: Contribution to journal › Article (journal) › peer-review
Open Access39 Citations (Scopus) -
Semliki Forest virus strain SFV6, complete genome
PATABENDIGE, A., Ferguson, M., Saul, S., Fragkoudis, R., Weisheit, S., Cox, J., Sherwood, K., Watson, M., Merits, A. & Fazakerley, J., 6 Aug 2015Research output: Other contribution
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2014
Arthropod-borne viral encephalitides
Solomon, T., PATABENDIGE, A. & Whitley, R., 29 May 2014, Infections of the Central Nervous System. p. 210-238 (Infections of the Central Nervous System ; vol. 4th).Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review
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EFFECT OF TYSABRI AND AQP4-IGG ON AN IN-VITRO MODEL OF BBB
PATABENDIGE, A., McQuaid, C. & Jacob, A., 9 May 2014, In: Journal of Neurology, Neurosurgery & Psychiatry. 85e4.Research output: Contribution to journal › Meeting Abstract › peer-review
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Primary porcine brain microvessel endothelial cell isolation and culture.
Patabendige, A. & Abbott, N., 8 Oct 2014, In: Current Protocols in Neuroscience. 69, p. 3.27.1-3.27.17 25297692 .Research output: Contribution to journal › Article (journal) › peer-review
18 Citations (Scopus) -
THE BBB IN ENCEPHALITIS: INFLAMMATION & A ROLE FOR STEROIDS?
PATABENDIGE, A., Defres, S., Keller, S., Vidyasagar, R., Michael, B. D., Das, K., Roberts, N., Parkes, L., Craig, A. G. & Solomon, T., 9 May 2014, In: Journal of Neurology, Neurosurgery & Psychiatry. 85e4.Research output: Contribution to journal › Meeting Abstract › peer-review
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2013
A detailed method for preparation of a functional and flexible blood-brain barrier model using porcine brain endothelial cells.
Patabendige, A., Skinner, R., Morgan, L. & Abbott, N., 12 Jul 2013, In: Brain Research. 1521, p. 16-30Research output: Contribution to journal › Article (journal) › peer-review
92 Citations (Scopus) -
Establishment of a simplified in vitro porcine blood-brain barrier model with high transendothelial electrical resistance.
Patabendige, A., Skinner, R. & Abbott, N., Jul 2013, In: Brain Research. 1521, p. 1-15Research output: Contribution to journal › Article (journal) › peer-review
121 Citations (Scopus) -
2012
Assays to predict drug permeation across the blood-brain barrier, and distribution to brain.
Abbott, N., Dolman, D. & Patabendige, A., 1 Mar 2012, In: Current Drug Metabolism. 9, 9, p. 901-910Research output: Contribution to journal › Article (journal) › peer-review
60 Citations (Scopus) -
The value of in vitro models of the blood-brain barrier and their uses.
Patabendige, A., 1 Dec 2012, In: Alternatives to laboratory animals : ATLA. 40, 6, p. 335-338Research output: Contribution to journal › Article (journal) › peer-review
16 Citations (Scopus) -
Toward a humanised alternative to the use of laboratory animals for blood-brain barrier research.
Patabendige, A., 1 Oct 2012, In: Alternatives to laboratory animals : ATLA. 40, 5, p. 12-13Research output: Contribution to journal › Article (journal) › peer-review
1 Citation (Scopus) -
2010
Structure and function of the blood-brain barrier.
Abbott, N., Patabendige, A., Dolman, D., Yusof, S. & Begley, D., Jan 2010, In: Neurobiology of Disease. 37, p. 1-13Research output: Contribution to journal › Article (journal) › peer-review
3851 Citations (Scopus)